Smart software aims to improve repeat heart ablation for AFib

NCT ID NCT05477147

Completed Disease control Sponsor: Volta Medical Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new approach for repeat catheter ablation in people with atrial fibrillation (AF) whose symptoms returned after a previous ablation. Doctors used a special software algorithm (VX1) to guide the procedure. The study included 96 adults and measured how many stayed free from AF episodes for one year after the repeat ablation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation guided by VX1 algorithm
What this could lead to: If successful, this approach could improve the success rate of repeat ablation procedures for atrial fibrillation, reducing the need for further treatments.
What could go wrong: This was a small, non-randomized study with no control group, so results may not be definitive. The procedure carries standard risks of catheter ablation, such as bleeding or heart rhythm issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Allegheny Health Network

Pittsburgh, Pennsylvania, 15212, United States
Arrhythmia Research Group

Jonesboro, Arkansas, 72401, United States
Ascension St. Vincent's Hospital

Jacksonville, Florida, 32204, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02241, United States
Clinique Pasteur

Toulouse, 31076, France
Deutsches Herzzentrum München

München, 80636, Germany
Grandview Medical Center

Birmingham, Alabama, 35243, United States
Houston Methodist Research Institute

Houston, Texas, 77030, United States
Hôpital Privé Jacques Cartier

Massy, 91300, France
Inova Fairfax Hospital

Fairfax, Virginia, 22042, United States
Kansas City Cardiac Arrhythmia Research LLC

Overland Park, Kansas, 66211, United States
Loyola University

Maywood, Illinois, 60152, United States
Northshore University Health System

Evanston, Illinois, 60201, United States
Northwell Health System

New York, New York, 11030, United States
Northwestern University

Evanston, Illinois, 60208, United States
OLV Aalst

Aalst, 9300, Belgium
Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States
The Ohio State University

Columbus, Ohio, 43210, United States
Washington University

St Louis, Missouri, 63130, United States

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