Smart software aims to improve repeat heart ablation for AFib

NCT ID NCT05477147

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new approach for repeat catheter ablation in people with atrial fibrillation (AF) whose symptoms returned after a previous ablation. Doctors used a special software algorithm (VX1) to guide the procedure. The study included 96 adults and measured how many stayed free from AF episodes for one year after the repeat ablation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

catheter ablation guided by VX1 algorithm

What this could lead to

If successful, this approach could improve the success rate of repeat ablation procedures for atrial fibrillation, reducing the need for further treatments.

What could go wrong

This was a small, non-randomized study with no control group, so results may not be definitive. The procedure carries standard risks of catheter ablation, such as bleeding or heart rhythm issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Allegheny Health Network

    Pittsburgh, Pennsylvania, 15212, United States

  • Arrhythmia Research Group

    Jonesboro, Arkansas, 72401, United States

  • Ascension St. Vincent's Hospital

    Jacksonville, Florida, 32204, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02241, United States

  • Clinique Pasteur

    Toulouse, 31076, France

  • Deutsches Herzzentrum München

    München, 80636, Germany

  • Grandview Medical Center

    Birmingham, Alabama, 35243, United States

  • Houston Methodist Research Institute

    Houston, Texas, 77030, United States

  • Hôpital Privé Jacques Cartier

    Massy, 91300, France

  • Inova Fairfax Hospital

    Fairfax, Virginia, 22042, United States

  • Kansas City Cardiac Arrhythmia Research LLC

    Overland Park, Kansas, 66211, United States

  • Loyola University

    Maywood, Illinois, 60152, United States

  • Northshore University Health System

    Evanston, Illinois, 60201, United States

  • Northwell Health System

    New York, New York, 11030, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • OLV Aalst

    Aalst, 9300, Belgium

  • Penn Presbyterian Medical Center

    Philadelphia, Pennsylvania, 19104, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • Washington University

    St Louis, Missouri, 63130, United States