Heart rhythm showdown: which ablation strategy wins for persistent AF?
NCT ID NCT05921734
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested two ways to treat persistent atrial fibrillation (a type of irregular heartbeat) using catheter ablation. In one group, doctors aimed to stop the abnormal rhythm during the procedure. In the other, they followed a preset plan and used electrical shock if needed. The trial included 480 adults having their first ablation. The goal was to see which approach led to fewer heart rhythm problems over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter ablation procedure
What this could lead to
If successful, this could help doctors choose the best ablation approach to reduce irregular heart rhythms in people with persistent atrial fibrillation.
What could go wrong
The trial is completed but results are not yet widely published. Ablation carries risks like bleeding, infection, or heart damage, and the best strategy may still depend on individual patient factors.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mu Qin
Shanghai, 200030, China
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Shanghai Chest Hospital
Shanghai, China