ATRIAL FIBRILLATION

This study compares two approaches to prevent atrial fibrillation (AFib) from returning. Researchers are testing whether combining a heart procedure (catheter ablation) with an intensive 12-week lifestyle program works better than the procedure alone. The trial involves 509 adult…

This study is testing whether personalized treatment decisions based on blood biomarker risk scores can better prevent strokes or death in people with atrial fibrillation compared to standard care. About 6,500 patients with this heart rhythm condition will be randomly assigned to…

This study is testing if a small device implanted in the heart (called WATCHMAN FLX) is a safe and effective alternative to taking daily blood-thinning pills for people with atrial fibrillation (AFib). The goal is to prevent strokes without the long-term risk of serious bleeding …

This study compares two established procedures for managing persistent atrial fibrillation (AF) in patients aged 75 and older. It tests whether a pacemaker implantation combined with a minor ablation (ABLATE) or a more extensive ablation (PVI) is better at reducing hospital stays…

This large study is testing whether a new oral blood thinner called milvexian works as well as the standard medication apixaban for preventing strokes in people with atrial fibrillation. Over 20,000 participants with irregular heart rhythms will take either milvexian or apixaban …

This study is testing the safety and performance of the CLAAS device, a small implant that closes off a part of the heart to prevent strokes. It is for people with atrial fibrillation who are at high risk of stroke but cannot take long-term blood thinners. Doctors will implant th…

This study is testing if a medication called liraglutide, which helps with weight loss, can improve the results of a standard heart procedure for atrial fibrillation (AFib). Researchers think the drug might work by reducing harmful fat deposits around the heart. The study will in…

This study planned to test a small heart implant called the LAmbre Plus device in people with atrial fibrillation who are at risk of stroke. The device is designed to seal off a small pouch in the heart where clots often form, offering an alternative to taking daily blood-thinnin…

This large registry study aims to gather real-world experience with a new pulsed field ablation technology for treating atrial fibrillation (AF). It will track 10,000 patients who receive this procedure to see how well it works, how safe it is, and how it affects their heart rhyt…

This study is collecting real-world information about how well the FARAPULSE pulsed field ablation system works for treating atrial fibrillation. Researchers are following about 1,173 patients across Europe who receive this treatment as part of their normal hospital care. The goa…

This study is testing if a personalized starting dose for the blood thinner heparin works better than the standard one-size-fits-all approach. It involves 145 adults being treated for blood clots or certain heart conditions. Researchers will see if using a formula based on a pati…

This study is testing the safety and effectiveness of a new medical device called the Arga Medtech CSE Ablation System. It uses electrical pulses to create scar tissue that blocks the faulty electrical signals causing atrial fibrillation (AFib). The study involves 25 patients who…

This study is testing if using a small, implanted heart monitor helps doctors better manage irregular heartbeats (atrial fibrillation or AFib) after a common procedure called catheter ablation. The monitor sends data to doctors, allowing for quicker treatment adjustments. The goa…

This study is observing how well a small, plug-like device works in real-world patients to prevent strokes. The device is implanted in the heart to seal off an area where dangerous blood clots can form in people with a common heart rhythm problem. Researchers are following over 6…

This study is testing a specific surgical technique, called a modified left atrial Maze procedure, performed at the same time as other planned heart surgery. The goal is to see if this technique is safe and effective at restoring and maintaining a normal heart rhythm in people wi…

This study is testing whether closing a small pouch in the heart, called the left atrial appendage, during planned open-heart surgery can reduce the risk of future strokes. It involves 1,500 patients who are having heart surgery for conditions like blocked arteries or valve probl…

This study aimed to compare two different heart ablation techniques for people with a type of irregular heartbeat called atrial fibrillation. It planned to test if a newer, more targeted ablation method using advanced mapping technology was faster, safer, or more effective than t…

This study is testing a new drug called HBI-3000, given as a single 30-minute IV infusion, to see if it can safely and effectively restore a normal heart rhythm in people who have recently developed atrial fibrillation (AF). The trial has two parts: first, to find the best dose, …

This study aims to find out which of three different surgical ablation techniques works best for controlling atrial fibrillation (irregular heartbeat) in patients who are already having heart surgery. Researchers will randomly assign 220 patients to receive one of three establish…

This study aims to see if a blood-thinning medication called edoxaban is safe and effective for preventing strokes in people who have both atrial fibrillation (an irregular heartbeat) and a history of bleeding in the brain. It will compare edoxaban to either taking no blood thinn…

This study compares two approaches for treating persistent atrial fibrillation, a common irregular heartbeat. Researchers are testing whether adding treatment for scar tissue in the heart's upper chamber works better than standard treatment alone. The trial involves 200 participa…

This study compares two blood-thinning drugs, Dabigatran and Warfarin, to see which is safer and more effective at preventing strokes in people with atrial fibrillation (an irregular heartbeat) who also have a narrowed heart valve called mitral stenosis. About 370 participants wi…

This study is looking at a safety device used during a procedure to treat a common irregular heartbeat called atrial fibrillation (AFib). The device cools the esophagus (the food pipe that runs behind the heart) to protect it from heat damage during the treatment. Researchers wan…

This study aims to see if long-term heart monitoring helps prevent second strokes in women who have had a stroke of unknown cause. It follows 1400 women to compare those who get a small implanted heart monitor with those who receive standard care. The goal is to see if finding hi…

This study aims to find the safest and most effective medication plan after implanting a device that helps prevent strokes in people with atrial fibrillation. It compares three different drug approaches: aspirin alone, a low-dose blood thinner, or a two-drug combination. The goal…

This study is testing whether a diabetes medication called metformin and lifestyle changes can reduce how often and how long patients experience atrial fibrillation (AFib). It involves 175 people who already have heart devices that can monitor their heart rhythm. Researchers want…

This large study is testing whether a small device implanted in the heart is as good as, or better than, daily blood thinner pills for preventing strokes in people with a common heart rhythm problem called atrial fibrillation. About 2,650 participants at high risk for stroke were…

This study is observing how an AI software program helps doctors during a procedure to treat atrial fibrillation, a common irregular heartbeat. The software helps identify specific areas of the heart to treat. Researchers are tracking 186 patients for two years to see if the AI-g…

This study is testing whether a small, implanted heart monitor can find hidden, irregular heartbeats (atrial fibrillation) in people with heart failure. Finding these rhythm problems early could allow doctors to start treatments like blood thinners to prevent strokes and hospital…

This study is testing a wireless, stick-on heart monitor to find brief, often symptomless episodes of an irregular heartbeat (atrial fibrillation) in hospitalized patients. Finding these hidden episodes helps doctors identify which patients are at high risk for having a stroke la…

This study is testing whether using an Apple Watch for long-term heart monitoring can help find hidden atrial fibrillation (an irregular heartbeat) in people at high risk for stroke. It will enroll 2,000 adults who show signs of possible hidden AFib on a special AI analysis of th…

This study is testing whether a home blood pressure monitor with a built-in heart rhythm sensor can accurately detect atrial fibrillation (AFib), a common irregular heartbeat. Researchers are comparing the device's readings against standard hospital ECG machines in 160 adults. Th…

This study is collecting real-world information on the safety and performance of a small, insertable heart monitor. The device continuously tracks heart rhythms to help doctors detect conditions like atrial fibrillation. Researchers are following 1,826 patients for one year to se…

This study is testing how well a Withings smartwatch can detect atrial fibrillation (AFib), a common irregular heartbeat. Researchers are comparing the watch's single-lead ECG reading to the standard 12-lead ECG used in hospitals. The goal is to see if the watch's automatic detec…

This study is testing a new method to find people at high risk for atrial fibrillation (AF), a common heart rhythm problem that can lead to stroke. It uses a computer-based risk score from health records to identify nearly 2,000 participants, who then receive remote heart monitor…

This study aimed to see if giving a short course of the drug amiodarone right after heart surgery could safely prevent a common complication called postoperative atrial fibrillation (an irregular heartbeat). It planned to test this in adults having certain types of heart surgery …

This study aims to find out if a common heart procedure for atrial fibrillation (AFib) truly reduces symptoms, or if the improvement is a powerful placebo effect. It will compare the standard procedure, which electrically isolates veins in the heart, against a carefully designed …

This study aims to better understand how often two effective leukemia drugs cause high blood pressure and irregular heartbeats. Researchers will give 50 patients smartwatches and home blood pressure monitors to track their heart health during treatment. The goal is to gather real…

This study aims to understand the genetic basis of atrial fibrillation, a common heart rhythm disorder. Researchers are collecting blood samples from 1,300 people with and without the condition to create a genetic database. The goal is to identify genes linked to the disease, whi…

This study is testing whether sending quarterly feedback emails to heart doctors helps them follow treatment guidelines more closely for patients with heart failure or atrial fibrillation. It involves about 7,000 patients who have visited a cardiology clinic recently. The goal is…

This study analyzed past medical records to understand how doctors treat patients with an irregular heartbeat (atrial fibrillation) who also have a high risk of stomach bleeding. Researchers looked at which blood thinners were prescribed and compared how often patients experience…

This study will follow 5,000 adults with persistent atrial fibrillation in Southwest China for five years to understand how different treatments work in real-world settings. Researchers will track which medications and procedures best prevent strokes, heart failure, and other com…

This study aims to understand why the standard treatment for atrial fibrillation (AFib) doesn't work for everyone. Researchers will create detailed computer models of patients' hearts to identify the unique electrical circuits causing their irregular heartbeat. The goal is to gat…

This study aims to identify patients at risk of developing irregular heartbeats after open-heart surgery. Researchers are testing whether special heart scans (wavECG and echocardiography) can predict which patients will experience these rhythm problems. The study observes 100 pat…

This study aims to understand if and how an irregular heartbeat (atrial fibrillation) causes short-term changes in thinking, memory, and decision-making. Researchers will compare how 600 patients perform on tablet-based thinking tests while their heart rhythm is irregular versus …