New alert system aims to prevent strokes in half a million heart patients

NCT ID NCT05236556

ENROLLING_BY_INVITATION Disease control Sponsor: University of Massachusetts, Worcester Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a computer alert in doctors' charts can help more atrial fibrillation patients get blood thinners to prevent strokes. About 5,094 patients and their doctors are involved. The alert fires during visits if a patient has high stroke risk but isn't on blood thinners, nudging the doctor to prescribe them.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Best practice advisory (BPA) alert system
What this could lead to: If successful, this could increase the number of atrial fibrillation patients who get blood thinners, reducing their stroke risk.
What could go wrong: This is a behavioral intervention, not a new drug, so its impact may be modest. The trial is large but relies on doctors following alerts, which may not always happen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation atrial flutter

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

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Locations

UMass Chan Medical School

Worcester, Massachusetts, 01655, United States
University of Florida College of Medicine - Jacksonville

Jacksonville, Florida, 32209, United States

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