Atrial flutter

This study tests whether closing a small pouch in the heart (the left atrial appendage) with a device is safer and as effective as long-term blood thinners for people with atrial fibrillation who have already had a brain bleed. About 530 participants will be randomly assigned to …

This study is testing the FARAPULSE Pulsed Field Ablation system in 376 people with persistent atrial fibrillation (AFib) who have already had a prior ablation. The device uses electrical pulses to destroy the heart tissue causing the abnormal rhythm. The goal is to see if it is …

This trial tests whether the position of the electrodes on the chest — front-to-back versus front-to-side — and applying manual pressure to the electrodes improve the success of electrical cardioversion for atrial fibrillation. About 1750 adults scheduled for non-urgent cardiover…

This study tests a monthly injection called abelacimab to prevent strokes in about 1,900 people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard oral blood thinners. Participants will receive either the drug or a placebo, and researchers will trac…

This study will compare two widely used blood thinners, apixaban (Eliquis) and rivaroxaban (Xarelto), in about 10,000 veterans with atrial fibrillation (an irregular heartbeat). The goal is to see which drug better prevents strokes and major bleeding. Participants must already be…

This trial tests a new way to treat typical atrial flutter, a heart rhythm problem. Instead of the standard linear ablation, doctors use a special catheter with tiny sensors to map and target only the high-voltage areas causing the flutter. The goal is to see if this approach is …

This study looks at whether it's safe to wait 5-9 days before treating a sudden episode of atrial fibrillation or flutter, instead of treating it right away in the emergency room. About 500 patients who are stable enough to go home will be randomly assigned to either immediate tr…

This study tests a new device called MAGiC that uses magnets to help doctors treat abnormal heart rhythms. About 150 adults who need a standard heart ablation procedure will take part. The goal is to see if the device is safe and works well, both right after the procedure and ove…

This study is testing a new catheter that uses real-time MRI to guide treatment for a common heart rhythm problem called type I atrial flutter. About 91 adults who need this procedure will receive radiofrequency ablation to block abnormal electrical signals. The main goals are to…

This study looks at whether starting treatment early for atrial fibrillation (AF) that is only detected by heart devices can help control the condition. About 520 adults with these hidden AF episodes will be randomly assigned to either early rhythm control therapy (medication, sh…

This study tests whether heart failure patients who fully recover after treatment for a fast heart rhythm (like atrial fibrillation) can safely stop their heart failure medications. 348 participants will be randomly assigned to either gradually stop their drugs or continue them a…

This study tests a new circular-shaped catheter that uses pulsed field energy to treat atrial fibrillation and atrial flutter. About 150 adults will receive the procedure, guided by ultrasound inside the heart. The goal is to see if the catheter safely and effectively blocks abno…

This study compares two types of portable heart monitors in people who have symptoms of an irregular heartbeat (arrhythmia) but whose standard heart test was normal. About 588 participants will wear either a continuous ECG patch or use a handheld ECG device for one month. The goa…

This study evaluates a new multichannel ECG system designed to detect early signs of cardiovascular disease (CVD) in people who may have no symptoms yet. The system uses advanced algorithms to analyze electrical signals from the heart, looking for subtle abnormalities that could …

This study tests whether a special CT scan done in the emergency department can quickly check for blood clots in people with atrial fibrillation or atrial flutter. If no clot is found, doctors can proceed with a procedure to restore normal heart rhythm (cardioversion) right away.…

This study tests whether an artificial intelligence (AI) system can help doctors spot hidden atrial fibrillation (AF) — a common heart rhythm disorder that raises stroke risk — by flagging suspicious electrocardiograms (ECGs). About 14,700 patients will be randomly assigned to ha…

This study tests whether giving fish oil through a vein during heart surgery can prevent a common complication called atrial fibrillation (irregular heartbeat) and help patients recover faster. About 550 high-risk adults having elective heart surgery will receive either fish oil …

This study tests a modified imaging catheter (ViewFlex X ICE) to help doctors see heart structures during procedures for irregular heartbeats. About 500 adults who are already scheduled for a heart procedure using ultrasound will be enrolled. The goal is to see if the new cathete…

This study looks at how a child's quality of life changes after a procedure called transcatheter ablation, which treats abnormal heart rhythms. Researchers will ask 200 children aged 5 to 17 and their parents to fill out questionnaires about physical, emotional, social, and schoo…

This study is testing a mobile app called Cardio2U for people with atrial fibrillation or heart failure. The app helps patients track their condition, learn about their disease, and communicate with their care team. Researchers will check if patients find the app easy to use and …

This study tests whether giving magnesium through an IV can safely slow a rapid heart rate in people with atrial fibrillation or flutter. Researchers will compare two different doses of magnesium to a placebo. The goal is to see if magnesium helps control heart rate within the fi…

This study involves 100 adults with heart rhythm problems who are already scheduled for a standard heart mapping procedure. Researchers will test new software features on the mapping system to see how well they work. The goal is to gather feedback to improve future versions of th…

This study will collect ECG recordings from 600 people using the HeartBeam 3-Lead ECG recorder. The goal is to build a database of heart rhythm information for future research and regulatory use. Participants will have their ECG taken as part of routine care, and their de-identif…

This study tests a new imaging system called VERAFEYE that helps doctors see inside the heart during a common procedure called catheter ablation. The procedure treats irregular heartbeats like atrial fibrillation. About 50 adults will take part to see if the system works well and…

This study is testing a new 3D imaging system that helps doctors see inside the heart during a procedure to treat atrial flutter and atrial fibrillation. About 50 adults who are already scheduled for a catheter ablation will have their procedure guided by this system. The goal is…

This study looks at whether scarring (fibrosis) in the heart's upper chambers can predict who will develop an irregular heartbeat after heart surgery. Researchers will track 50 adults aged 40+ with no prior irregular heartbeat who are scheduled for heart surgery. The goal is to s…

This study compares two catheters used during a common heart procedure for atrial fibrillation. The goal is to see if one catheter can confirm that the treatment worked faster than the current method. Thirty adults with persistent atrial fibrillation or atrial flutter will be enr…

This study aims to improve how doctors predict the risk of sudden cardiac death or heart failure in people with inherited heart diseases. Researchers will use artificial intelligence to analyze data from 1,000 participants, including medical history, ECGs, imaging, genetic tests,…

This study looks at how belly pressure changes during a heart procedure called pulsed field ablation for atrial fibrillation. Researchers will use a special catheter to measure pressure in the abdomen while patients are under different types of anesthesia. The goal is to see if t…

This study looks at whether MRI scans can help predict serious heart events in people who have implanted heart devices like pacemakers or defibrillators. Researchers will scan 1,500 adults before they get their device and track their health for years. The goal is to see if MRI fi…

This registry collects information from 1,000 patients who have had or will have a heart rhythm procedure at University Hospital Düsseldorf. The goal is to track safety and success of these standard procedures in everyday care. No new treatments are being tested; instead, researc…

This study is testing a special heart monitor, the BIOMONITOR IV, in 300 people with heart failure who also have irregular heartbeats. The device tracks heart activity, fluid levels, and breathing patterns to see if it can predict when heart failure gets worse. Researchers hope t…