Simple changes to electrode placement could boost heart shock success
NCT ID NCT05511389
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This trial tests whether the position of the electrodes on the chest — front-to-back versus front-to-side — and applying manual pressure to the electrodes improve the success of electrical cardioversion for atrial fibrillation. About 1750 adults scheduled for non-urgent cardioversion will be randomly assigned to one of the two electrode positions. Those who remain in atrial fibrillation after the first shock will then be randomly assigned to receive manual pressure or not. The goal is to see which approach restores normal heart rhythm more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electrical cardioversion with different electrode positions and manual pressure
- What this could lead to
- If successful, this trial could establish a simple, low-cost technique to improve cardioversion success, reducing the need for additional medications or invasive procedures for many patients with atrial fibrillation.
- What could go wrong
- This is a single trial testing two modifications to a standard procedure; results may not show a meaningful difference, or benefits may not apply to all patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,750 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2023
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Consenting adult patients scheduled for non-emergent electrical cardioversion of Atrial Fibrillation or Flutter Exclusion Criteria: 1. Insufficiently anticoagulation for cardioversion as per Canadian Cardiovascular Society guidelines or have not undergone trans-esophageal echocardiography to rule out left atrial thrombus 2. Anatomic contraindication to anterolateral or anteroposterior placement (e.g. skin conditions or wounds)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8L2X2, Canada
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Institut Universitaire De Cardiologie Et De Pneumologie de Québec
RECRUITINGQuébec, Quebec, Canada
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Institut de cardiologie de Montréal
ACTIVE_NOT_RECRUITINGMontreal, Quebec, Canada
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Women's College Hospital
RECRUITINGToronto, Ontario, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can dropping one blood thinner cut bleeding without raising heart risks?
- Hidden heart rhythm problems after stroke: can longer monitoring prevent a second stroke?
- Can a blood test reveal why atrial fibrillation returns after cryoablation?