New heart device aims to tame stubborn AFib

NCT ID NCT06735534

Recruiting now Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 28, 2026 · Updated 5 times

Summary

This study is testing the FARAPULSE Pulsed Field Ablation system in 376 people with persistent atrial fibrillation (AFib) who have already had a prior ablation. The device uses electrical pulses to destroy the heart tissue causing the abnormal rhythm. The goal is to see if it is safe and effective for a repeat procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FARAPULSE Pulsed Field Ablation System (a device that uses electrical pulses to destroy heart tissue causing abnormal rhythms)
What this could lead to: If successful, this could provide a safe and effective way to treat persistent atrial fibrillation in people who have already had a prior ablation, potentially reducing the need for long-term medication.
What could go wrong: This is an early-stage, single-arm study with no comparison group, so results may not be definitive. Risks include procedure-related complications like bleeding, heart damage, or stroke.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac atrial fibrillation atrial flutter persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERSISTENT ATRIAL FIBRILLATION

Contacts and locations

Locations

AdventHealth Orlando-Hospital
RECRUITING

Orlando, Florida, 32803, United States
AdventHealth Tampa-Hospital
RECRUITING

Tampa, Florida, 33613, United States
Advocate Christ Medical Center-Hospital
RECRUITING

Oak Lawn, Illinois, 60453, United States
Arrhythmia Research Group-Research Facility
RECRUITING

Jonesboro, Arkansas, 72401, United States
Atrium Health Navicent The Medical Center
RECRUITING

Macon, Georgia, 32201, United States
Bethesda North Hospital
RECRUITING

Cincinnati, Ohio, 45242, United States
Christus Trinity Mother Frances Health System
RECRUITING

Tyler, Texas, 75701, United States
Dartmouth Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
HCA Florida Mercy Hospital
RECRUITING

Miami, Florida, 33133, United States
John Hunter Hospital
RECRUITING

New Lambton Heights, New South Wales, 606-8507, Australia
Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Lovelace Medical Center
RECRUITING

Albuquerque, New Mexico, 87102, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Memorial Health University Medical Center
RECRUITING

Savannah, Georgia, 31404, United States
Mobile Infirmary Medical Center
RECRUITING

Mobile, Alabama, 36607, United States
Naples Comprehensive Health
RECRUITING

Naples, Florida, 34102, United States
National Taiwan University Hospital
RECRUITING

Taipei, Taiwan
Northwell Health
RECRUITING

Manhasset, New York, 11030, United States
Ohio State University Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
Oklahoma Heart Institute
RECRUITING

Tulsa, Oklahoma, 74104, United States
Sentara Norfolk General Hospital
RECRUITING

Norfolk, Virginia, 23507, United States
South Denver Cardiology Associates, PC
RECRUITING

Littleton, Colorado, 80120, United States
Southcoast Physicians Group
RECRUITING

Fall River, Massachusetts, 02720, United States
St. Andrew's War Memorial Hospital
RECRUITING

Brisbane, Queensland, 4001, Australia
St. John's Regional Medical Center
RECRUITING

Oxnard, California, 93030, United States
St. Luke's Boise Medical Center
RECRUITING

Boise, Idaho, 83712, United States
St. Mark's Hospital
RECRUITING

Salt Lake City, Utah, 84124, United States
Stanford University Medical Center
RECRUITING

Stanford, California, 94305, United States
Taipei Veterans General Hospital
RECRUITING

Taipei, Taiwan
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States
Texas Cardiac Arrhythmia Research
RECRUITING

Austin, Texas, 78705, United States
The Alfred Hospital
RECRUITING

Melbourne, Australia
The Royal Melbourne Hospital
RECRUITING

Parkville, Victoria, 3050, Australia
Trident Medical Center
RECRUITING

Charleston, South Carolina, 29406, United States
University of Southern California Hospital
RECRUITING

Los Angeles, California, 90033, United States
Victorian Heart Hospital
RECRUITING

Clayton, Victoria, 3168, Australia
Virtua Health Inc.
RECRUITING

Marlton, New Jersey, 08053, United States
Weill Cornell Medical University
RECRUITING

New York, New York, 10065, United States
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia
William Beaumont Hospital-Hospital
RECRUITING

Royal Oak, Michigan, 48073, United States

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