Extra ablation target may cut AF recurrence in persistent cases
NCT ID NCT06929897
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This trial tests whether adding posterior wall isolation to standard pulmonary vein isolation reduces atrial fibrillation recurrence in people with persistent AF. About 482 adults aged 20 to 80 will be randomly assigned to one of the two procedures using pulsed-field energy. Participants will be followed for 12 months to check for any return of abnormal heart rhythms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pulmonary vein isolation with or without posterior wall isolation using pulsed-field ablation
- What this could lead to
- If successful, adding posterior wall isolation could become a standard approach to lower atrial fibrillation recurrence in patients with persistent AF.
- What could go wrong
- This is a single-center trial, and results may not apply to all patients. Adding extra ablation could increase complication risks without clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ewha Womans University Mokdong Hospitoal
Seoul, South Korea
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