Massive VA study to settle debate: which blood thinner is safer for A-Fib?

NCT ID NCT06953726

Recruiting now Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two widely used blood thinners, apixaban (Eliquis) and rivaroxaban (Xarelto), in about 10,000 veterans with atrial fibrillation (an irregular heartbeat). The goal is to see which drug better prevents strokes and major bleeding. Participants must already be taking one of these medications, and all data will be collected from medical records over about 7 years.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation atrial flutter Hemorrhage Ischemic Stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Boston VA CSP Coordinating Center
RECRUITING

Boston, Massachusetts, 02111, United States
Miami VA Healthcare System, Miami, FL
RECRUITING

Miami, Florida, 33125, United States
Minneapolis VA Call Center
RECRUITING

Minneapolis, Minnesota, 55417, United States
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
NOT_YET_RECRUITING

Boston, Massachusetts, 02130-4817, United States
VA Portland Health Care System, Portland, OR
RECRUITING

Portland, Oregon, 97207-2964, United States

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