New risk score tool aims to cut strokes in heart condition patients
NCT ID NCT03753490
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether using a personalized risk score (ABC-score) to guide treatment can lower the chance of stroke or death in people with atrial fibrillation, a common heart rhythm problem. About 3,900 participants are randomly assigned to either standard care or treatment based on their ABC-risk scores. The goal is to see if tailored recommendations for blood thinners and other therapies improve survival without major bleeding.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ABC score-guided therapy (personalized treatment recommendations based on biomarker-based risk scores)
- What this could lead to
- If successful, this could provide a more effective way to prevent strokes and deaths in people with atrial fibrillation by tailoring treatments to individual risk.
- What could go wrong
- This is a large trial but still early in testing a decision-support tool, not a drug. The approach may not significantly improve outcomes over standard care, and results may not apply to all patient groups.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Uppsala University Hospital
Uppsala, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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