Heart rhythm showdown: which procedure keeps seniors out of hospital?

NCT ID NCT04906668

Ongoing Disease control Sponsor: St. Josefs-Hospital Wiesbaden GmbH Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two procedures for people aged 75 and older with persistent atrial fibrillation (an irregular heartbeat). One group gets a pacemaker plus ablation of the heart's electrical node, while the other gets pulmonary vein isolation using cryoenergy. The goal is to see which approach reduces hospital stays and improves quality of life. The trial involves 196 participants across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show which procedure better reduces hospitalizations and improves quality of life for elderly patients with persistent atrial fibrillation.
What could go wrong: This is a relatively small trial (196 participants) and results may not apply to all elderly patients. Both procedures carry risks like bleeding or infection, and one group may need additional treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Asklepios Klinik St. Georg

Hamburg, Germany
Ev. Krankenhaus Hagen-Haspe

Hagen, Germany
Kerckhoff-Klinik Bad Nauheim

Bad Nauheim, Germany
Klinikum Fürth

Fürth, Germany
Krankenhaus Landshut-Achdorf

Landshut, Germany
St. Josefs-Hospital Wiesbaden GmbH

Wiesbaden, 65189, Germany
Universitätsklinikum Essen

Essen, Germany
Universitätsklinikum Frankfurt am Main

Frankfurt, Germany
Universitätsklinikum Innsbruck

Innsbruck, Austria
Universitätsklinikum Münster

Münster, Germany
Vivantes Klinikum am Urban

Berlin, Germany
Westpfalz-Klinikum Kaiserslautern

Kaiserslautern, Germany

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