Heart rhythm showdown: which procedure keeps seniors out of hospital?

NCT ID NCT04906668

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two procedures for people aged 75 and older with persistent atrial fibrillation (an irregular heartbeat). One group gets a pacemaker plus ablation of the heart's electrical node, while the other gets pulmonary vein isolation using cryoenergy. The goal is to see which approach reduces hospital stays and improves quality of life. The trial involves 196 participants across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show which procedure better reduces hospitalizations and improves quality of life for elderly patients with persistent atrial fibrillation.

What could go wrong

This is a relatively small trial (196 participants) and results may not apply to all elderly patients. Both procedures carry risks like bleeding or infection, and one group may need additional treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation persistent atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asklepios Klinik St. Georg

    Hamburg, Germany

  • Ev. Krankenhaus Hagen-Haspe

    Hagen, Germany

  • Kerckhoff-Klinik Bad Nauheim

    Bad Nauheim, Germany

  • Klinikum Fürth

    Fürth, Germany

  • Krankenhaus Landshut-Achdorf

    Landshut, Germany

  • St. Josefs-Hospital Wiesbaden GmbH

    Wiesbaden, 65189, Germany

  • Universitätsklinikum Essen

    Essen, Germany

  • Universitätsklinikum Frankfurt am Main

    Frankfurt, Germany

  • Universitätsklinikum Innsbruck

    Innsbruck, Austria

  • Universitätsklinikum Münster

    Münster, Germany

  • Vivantes Klinikum am Urban

    Berlin, Germany

  • Westpfalz-Klinikum Kaiserslautern

    Kaiserslautern, Germany