New IV drug aims to jolt atrial fibrillation back to normal rhythm in minutes

NCT ID NCT04680026

Ongoing Disease control Sponsor: HUYABIO International, LLC. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single 30-minute IV infusion of HBI 3000 in 150 adults with atrial fibrillation that started within the last 3 days. The goal is to safely convert the heart back to normal rhythm. The trial first finds the best dose, then compares it to a placebo in a blinded fashion.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

CHRISTUS Trinity Mother Frances Hospital - Tyler

Tyler, Texas, 75701, United States
Centre hospitalier de L'Universite de Montral (CHUM)

Montreal, Quebec, H2X 0C1, Canada
Centre integre de sante et de services sociaux de Lanaudiere - Hopital Pierre-Le Gardeur

Terrebonne, Quebec, J6V 2H2, Canada
Dedinje Institute for Cardiovascular Diseases

Belgrade, 11040, Serbia
Montreal Heart Institute

Montreal, Quebec, H1T 1C8, Canada
NCH Research Institute

Naples, Florida, 34102, United States
Niš University Clinical Center

Niš, Bulevar Doktora, 18108, Serbia
North Mississippi Medical Center

Tupelo, Mississippi, 38801, United States
Prairie Education & Research

Springfield, Illinois, 62701, United States
University Clinical Center of Serbia

Belgrade, 11000, Serbia
University Clinical Center of the Republic of Srpska

Banja Luka, 78000, Bosnia and Herzegovina
University Hospital Medical Center Bezanijska kosa

Belgrade, 11080, Serbia
Waikato Hospital

Hamilton, 3240, New Zealand
Wellington Regional Hospital

Wellington, 6021, New Zealand

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