New infusion drug aims to stop irregular heartbeat in its tracks
NCT ID NCT04680026
First seen Dec 16, 2025 · Last updated May 16, 2026 · Updated 20 times
Summary
This study tests a single 30-minute IV infusion of HBI 3000 in 150 adults aged 18–80 who have had atrial fibrillation (irregular heartbeat) for 2 to 72 hours. The goal is to see if the drug can safely and quickly convert the heart back to normal rhythm. The trial first finds the best dose in an open-label phase, then compares two doses against a placebo in a blinded phase.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRISTUS Trinity Mother Frances Hospital - Tyler
Tyler, Texas, 75701, United States
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Centre hospitalier de L'Universite de Montral (CHUM)
Montreal, Quebec, H2X 0C1, Canada
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Centre integre de sante et de services sociaux de Lanaudiere - Hopital Pierre-Le Gardeur
Terrebonne, Quebec, J6V 2H2, Canada
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Dedinje Institute for Cardiovascular Diseases
Belgrade, 11040, Serbia
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Montreal Heart Institute
Montreal, Quebec, H1T 1C8, Canada
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NCH Research Institute
Naples, Florida, 34102, United States
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Niš University Clinical Center
Niš, Bulevar Doktora, 18108, Serbia
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North Mississippi Medical Center
Tupelo, Mississippi, 38801, United States
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Prairie Education & Research
Springfield, Illinois, 62701, United States
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University Clinical Center of Serbia
Belgrade, 11000, Serbia
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University Clinical Center of the Republic of Srpska
Banja Luka, 78000, Bosnia and Herzegovina
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University Hospital Medical Center Bezanijska kosa
Belgrade, 11080, Serbia
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Waikato Hospital
Hamilton, 3240, New Zealand
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Wellington Regional Hospital
Wellington, 6021, New Zealand
Conditions
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