Zapping heart rhythm problems: new device uses electrical pulses to treat AFib
NCT ID NCT05572047
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests a new device that uses special electrical pulses (coherent sine-burst electroporation) to treat atrial fibrillation, a common heart rhythm problem. The device aims to isolate the pulmonary veins, which are often the source of the abnormal signals. The study will enroll 25 people with paroxysmal or persistent AFib who have not responded to medication, to see if the procedure is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Coherent sine-burst electroporation (CSE) ablation system (device)
What this could lead to
If successful, this could offer a new, potentially safer way to treat atrial fibrillation by using targeted electrical pulses instead of heat or cold to destroy abnormal heart tissue.
What could go wrong
This is a very early pilot study with only 25 people, so results may not apply to everyone. The procedure carries risks like any heart ablation, including serious side effects. It is not yet proven to be better than existing treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Israeli-Georgian Medical Research Clinic Helthycore Ltd
Tbilisi, 0112, Georgia
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KBC Zagreb
Zagreb, HR-10 000, Croatia
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University Hospital of Split
Split, 21 000, Croatia