New device aims to seal off stroke risk without blood thinners
NCT ID NCT06580275
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new device called CLAAS that is implanted in the heart to close off a small pouch (the left atrial appendage) where blood clots often form in people with atrial fibrillation. The goal is to reduce the risk of stroke without needing long-term blood thinners. About 80 adults with atrial fibrillation and a high stroke risk who cannot take blood thinners will receive the implant, and doctors will check if the device seals properly and is safe after 45 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CLAAS device (a heart implant to close the left atrial appendage)
What this could lead to
If successful, this device could offer a safer, drug-free way to prevent strokes in people with atrial fibrillation who cannot use blood thinners.
What could go wrong
This is an early-stage study with only 80 participants and no comparison group, so results may not apply broadly. Risks include heart injury, stroke, bleeding, or the device not sealing properly.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Aarhus University Hospital, Skejby
Aarhus, DK-8200, Denmark
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Fondazione Toscana Gabriele Monasterio
Massa, 54100, Italy
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Na Homolce Hospital
Prague, 150 30, Czechia
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University Hospital of Copenhagen
Copenhagen, DK-2100, Denmark