END STAGE RENAL DISEASE

This study tested a portable device called the Carry Life UF system for people with end-stage kidney disease who use peritoneal dialysis at home. The device is designed to be used during a standard dialysis session to help remove more excess fluid from the body. Researchers compa…

This study tested the safety and performance of a new type of hemodialyzer called ELISIO-HX. It involved 22 adults with end-stage kidney disease who were already on regular dialysis. Researchers checked if the device could effectively remove a specific waste product from the bloo…

This study tested two different safety programs to reduce episodes of low blood pressure during dialysis treatments for people with kidney failure. Researchers worked with 20 dialysis clinics to see if training healthcare teams or connecting patients with peer mentors could make …

This study monitored the safety of a home dialysis machine called HemoCare for people with kidney failure. It allowed 25 patients who had already tested the system to continue using it at home while the device was being reviewed for market approval. The main goal was to track any…

This study tested a new type of dialysis filter called the Clearum HS to see how well and safely it works for people with end-stage kidney disease. Twenty patients on regular dialysis first used a standard filter for two weeks, then switched to the new Clearum filter for six week…

This study tested whether giving oral vitamin C to patients with kidney failure on regular dialysis could safely help control their anemia. It involved 60 patients to see if the vitamin could reduce the amount of a standard anemia medication (erythropoietin) they needed. The goal…

This early-stage study tested a single injection of an experimental drug called MK-2060 in people with advanced kidney disease. The main goals were to check the drug's safety, see how long it stays in the body, and measure its effect on blood clotting. Only 14 people with stage 4…

This study tested whether a simple hand grip exercise program could help dialysis fistulas develop properly and stay open longer. Patients on dialysis were randomly assigned to either do hand grip exercises with a special device for six weeks or receive standard care. Researchers…

This study tested whether kidneys from deceased donors infected with hepatitis C could be safely transplanted into patients without the virus. After the transplant, recipients received antiviral medication to clear the hepatitis C infection. Researchers compared the health of the…

This study tested whether trained transplant recipients, acting as 'navigators,' could help other kidney failure patients complete the many steps needed to get a transplant. It involved about 170 adult patients on dialysis, comparing those who received help from a navigator with …

This study tested a small, drug-releasing implant placed during surgery to create a dialysis access point (called a fistula). The goal was to see if the implant, compared to standard surgery, could help the fistula develop better and last longer for patients on kidney dialysis. A…

This study tested whether a small, drug-releasing implant placed during surgery could improve the success of creating a usable dialysis access point (called a fistula) in the arm. It involved 269 people with kidney failure who needed to start or were recently on dialysis. Researc…

This study compared a new lab-made blood vessel against standard surgery for creating dialysis access in people with kidney failure. Researchers tested whether the engineered vessel works as well as the patient's own vein for connecting to dialysis machines. The goal was to provi…

This study tested whether an experimental drug called MK-2060 could prevent dangerous blood clots from forming in the artificial grafts used for dialysis in people with kidney failure. Over 500 participants received either one of two doses of the drug or a placebo to see which wo…

This study tested whether a special communication tool called 'Best Case/Worst Case' helps doctors have better conversations with older patients who have severe, permanent kidney failure. The tool helps doctors and patients talk about future care options, quality of life, and end…

This study tested whether a 26-week exercise and education program could help people on long-term dialysis feel better. Researchers compared 133 patients who either did the exercise program during their dialysis sessions or received standard care. The goal was to see if regular e…

This study tested a program called SPIRIT, designed to help patients with end-stage kidney disease and their chosen family members plan for difficult end-of-life care decisions. The program involved two guided conversations with a trained dialysis care provider. Researchers wante…

This study tested a new communication program designed to help older adults with advanced kidney disease make better decisions about starting dialysis. Doctors received special training, and patients got coaching to help them talk about their values and preferences. The goal was …

This study explored how kidney specialists think about involving patients in choosing their dialysis treatment. Researchers interviewed 25 active kidney doctors across Belgium to understand their beliefs, attitudes, and the challenges they face when discussing options like home d…

This study tested a new education program for patients waiting for a kidney transplant. The program teaches patients and their chosen friends or family members (called 'Live Donor Champions') about living kidney donation. The goal was to see if this program could be successfully …