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Simple supplement may fight fatigue in kidney dialysis patients

NCT ID NCT05705414

First seen Jan 09, 2026 · Last updated Jun 21, 2026 · Updated 18 times

Summary

This early-phase study tests whether taking amino acid supplements during dialysis can reduce fatigue, frailty, and improve thinking in people with end-stage kidney disease. Researchers will compare a single amino acid (valine) with a mix of essential amino acids in 28 patients. The goal is to see if these supplements can improve quality of life for those on long-term dialysis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

amino acid supplements (valine or essential amino acid blend)

What this could lead to

If it works, this could point toward a simple supplement to help dialysis patients feel less tired and stronger.

What could go wrong

This is a very early, small trial with only 28 people. The supplements may not help, or benefits may be too small to notice.

Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.