Can amino acids boost energy for kidney patients on dialysis?

NCT ID NCT05705414

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This early-phase study tests whether taking amino acid supplements during dialysis can reduce fatigue, frailty, and improve thinking in people with end-stage kidney disease. Researchers will compare a single amino acid (valine) with a mix of essential amino acids in 28 adults on hemodialysis. The goal is to see if these supplements can help patients feel more energetic and stronger.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Amino acid supplements (valine or essential amino acids)
What this could lead to
If it works, this could point toward a simple, safe way to ease fatigue and improve quality of life for people on dialysis.
What could go wrong
This is a very small, early-phase trial with only 28 participants. The supplements may not work better than placebo, and results may not apply to all dialysis patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

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