END STAGE RENAL DISEASE

This study tests a new automated ultrasound system (EchoMark/EchoSure) to see if it can help arteriovenous fistulas mature faster in people with end-stage kidney disease. About 304 adults will be randomly assigned to get biweekly automated scans or standard care. The goal is to s…

This study tests whether kidney transplants from HIV-positive donors are safe and effective for HIV-positive patients with kidney failure. About 30 adults with well-controlled HIV will receive a kidney from an HIV-positive donor. The goal is to see if these transplants work as we…

This study tests a special wrap called SelfWrap placed around blood vessels during fistula creation for dialysis. It aims to help the fistula mature faster and work without extra procedures. About 600 adults with chronic kidney disease needing a new fistula will take part and be …

This study tests a device called VasQ, which is placed around a blood vessel connection (fistula) used for dialysis. The goal is to see if VasQ helps the fistula work well for dialysis sooner and longer than standard surgery. About 300 adults with kidney failure will be randomly …

This study looks at whether adjusting salt levels during dialysis can help people with kidney failure feel better and have fewer complications. About 130 adults on hemodialysis will either receive standard care or a personalized sodium management program. The goal is to see if th…

This study is testing a device called the BD WavelinQ EndoAVF System, which creates a connection between an artery and a vein in the arm to make dialysis easier. About 280 adults with end-stage kidney disease who need dialysis will take part. The goal is to see if the device work…

This study tests a drug called pegcetacoplan in 320 adults who are getting a kidney transplant from a deceased donor and are at high risk for delayed graft function (when the kidney takes a while to start working). Participants receive either the drug or a placebo after surgery. …

This study looks at whether a special ultrasound inside the vein (IVUS) can find blockages better than the usual X-ray method in people with kidney failure who are on dialysis. About 50 patients will be checked during a routine procedure. The goal is to see if IVUS gives clearer …

This study tests whether having dialysis patients regularly report their symptoms electronically, and sending those results to their care team, can improve their quality of life. About 2,293 adults with end-stage renal disease on dialysis in France will take part. The goal is to …

This study tests a program called CAPABLE Transplant to help people with kidney failure who are waiting for a transplant. The program addresses barriers like frailty, depression, and lack of support to help them become active on the waitlist. About 43 adults will participate to s…

This study looks at whether adding a supplement called CoQ10 to a special exercise program can help people with end-stage kidney disease build muscle and move better. Many patients on dialysis become frail, and exercise alone often doesn't help enough. The trial will test if CoQ1…

This study looks at how inflammation from type 2 diabetes, end-stage kidney disease, or irritable bowel syndrome can change the way the body processes certain drugs. Researchers will collect blood samples from 150 adults and children to measure inflammation markers and immune cel…

This study is a large registry that will collect health information from 60,000 people with both heart and kidney disease. The goal is to learn more about how these conditions interact and what factors affect patient outcomes. No new treatments are being tested; instead, research…

This study is testing a web-based app that helps people waiting for a kidney or liver transplant share their story on social media to find a living donor. The goal is to see if this approach increases the number of potential donors who come forward and leads to more transplants. …