END STAGE RENAL DISEASE

This study tests whether giving specific blood pressure drugs based on real-time heart and vessel measurements can improve fluid management during kidney transplant surgery. Researchers will assign 255 adults to receive vasopressin, norepinephrine, calcium chloride, or dopamine d…

This early-stage trial tests whether giving kidney transplant recipients a special treatment made from their donor's cells, combined with a light-based therapy called photopheresis, can safely reduce the risk of organ rejection. About 24 adults receiving their first kidney transp…

This study tests whether adding levocarnitine injections to standard care can reduce the amount of anemia medication needed by people on kidney dialysis. About 94 adults on long-term dialysis will receive either levocarnitine after each session or usual care alone for 6 months. T…

This study tests whether wearing virtual reality (VR) glasses during needle insertion can reduce pain and anxiety in hemodialysis patients. 150 adults with end-stage kidney disease will either receive standard care or watch a calming 360-degree underwater video through VR goggles…

This study tests whether doing progressive relaxation exercises at times matched to each patient's natural circadian rhythm can help manage symptoms, improve sleep quality, increase comfort, and boost mental well-being in people receiving hemodialysis. Researchers will enroll 75 …

This study tests whether a smartphone app that guides patients through acupressure can reduce fatigue, itching, and improve sleep in people on hemodialysis. About 70 adults who have been on dialysis for at least three months will be randomly assigned to use the app daily for four…

This early-stage study tests whether bupropion, a medicine used for smoking cessation and depression, can reduce severe tiredness in people with end-stage kidney disease on dialysis. Sixteen participants will take bupropion three times a week for 8 weeks and report their fatigue …

This study looks at whether combining relaxation exercises with listening to a specific chapter of the Quran (Surah Ar-Rahman) can help people on kidney dialysis feel less anxious, sleep better, and improve their vital signs. 76 adults with advanced kidney disease who are on regu…

This study tests if simple eye exercises done during dialysis sessions can help kidney patients improve their balance and reduce their risk of falling. The study will include 30 adults on dialysis. Researchers will check if the exercises are safe and easy to do, and if they show …

This study looks at whether doing joint range-of-motion exercises and Benson relaxation techniques during dialysis can improve how well the treatment works, help patients follow their care plan, and boost quality of life. About 72 adults on long-term hemodialysis will take part. …

This study will check if men and women on hemodialysis have different balance abilities. About 155 patients will do two simple tests: standing up from a chair and walking a short distance. No treatment is given — the goal is just to understand how balance may differ between gende…

This study tests whether a digital program (videos, texts, and optional phone support) can help people with kidney failure get more inquiries from potential living donors. About 430 adults referred for a kidney transplant will be randomly assigned to get the program with or witho…

This study will survey 160 adults on long-term hemodialysis at Sohag University Hospital to find out how many experience anxiety or depression. Researchers will also look for links to age, gender, and other health factors. The goal is to better understand the mental health needs …

This study surveys 200 adults (patients and caregivers) to learn what matters most when moving from peritoneal dialysis at home to hemodialysis in a clinic. The goal is to improve care and support during this transition. No treatments or medications are tested—only opinions and p…

This study looks at why dialysis patients often have heart problems that are hard to detect. Researchers will use a special heart test during a routine procedure to check for tiny blood vessel issues in 30 adults who have been on dialysis for at least 6 months. The goal is to fin…

This study looks at two standard methods of stitching the kidney artery during a living donor kidney transplant: interrupted sutures and continuous sutures. Researchers will review past cases and follow 70 new adult patients at Assiut University to see which technique leads to sh…

This study looks at whether information from a machine that preserves donated kidneys can help predict how well the kidney will work after transplant. Researchers will collect data from 300 people receiving kidneys from older or higher-risk donors. The goal is to improve organ ma…

This early study tests a wearable device that listens to the sound of blood flow in the arm of people on dialysis. The goal is to see if the device can accurately measure the same signals as a standard stethoscope. Six adults with mature fistulas will wear the device weekly for 8…

This study explores how Black and Caucasian patients with kidney disease communicate with their transplant doctors during evaluation visits. Researchers will record these conversations and survey patients to find out which communication styles lead to more living donor referrals …