END STAGE RENAL DISEASE

This study tests whether adding a special filter (hemoperfusion) to regular dialysis can better remove harmful substances like beta-2 microglobulin, parathyroid hormone, and C-reactive protein from the blood of people with end-stage kidney disease. About 410 adults on maintenance…

This study looks at whether people with ANCA vasculitis who have reached kidney failure can safely stop taking immunosuppressive medications. The goal is to see if stopping these drugs reduces serious infections and other complications without causing dangerous disease flare-ups.…

This study tests a one-month treatment for latent tuberculosis (TB) in people waiting for a kidney transplant. The goal is to see if the treatment is safe and easy to complete. 25 adults with end-stage kidney disease and latent TB will take the medication and be monitored for sid…

This study compares a new surgical method (RADAR) to the standard one for creating a blood vessel connection in the wrist for dialysis. The goal is to see if the new technique helps the access work better and last longer. About 200 adults with end-stage kidney disease who need a …

This study is testing a new device called the aXess graft for people with end-stage kidney disease who need hemodialysis but cannot have a standard fistula. The graft creates a connection between an artery and a vein to allow easy access for dialysis. The study will check how saf…

This study tests a new device called STARgraft-3, a special tube used to connect an artery to a vein for hemodialysis in people with end-stage kidney disease. The goal is to see if it works better than standard grafts at preventing blockages and infections. About 15 adults who ne…

This study is testing a virtual health platform that provides exercise, nutrition advice, and psychological support to people undergoing hemodialysis for end-stage kidney disease. The goal is to help patients feel better and improve their walking ability and overall quality of li…

This study looks at whether a special education program can help veterans with advanced chronic kidney disease learn more about their condition and make better choices about dialysis. About 656 veterans will take part, with some receiving the education and others getting usual ca…

This study is a long-term follow-up for 11 kidney transplant patients who previously received an experimental cell therapy (CAR-Treg) designed to help the body accept the new kidney. Researchers will track safety and side effects for up to 15 years after the infusion. The goal is…

This study looks at whether urine tests can detect signs of kidney transplant rejection or damage in children. Researchers are checking if certain substances in urine can give the same information as a kidney biopsy, which is more invasive. The goal is to make monitoring easier a…