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Pumpkin seed oil may fight inflammation in kidney patients — a trial puts it to the test

NCT ID NCT06314243

Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether daily pumpkin seed oil supplements can reduce inflammation, oxidative stress, and unhealthy blood fats in people undergoing hemodialysis. Researchers will compare a group taking the oil with a group that does not, measuring markers like interleukin-6 and malondialdehyde. The goal is to see if this natural supplement could improve health outcomes for patients with kidney failure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pumpkin seed oil dietary supplement
What this could lead to
If it works, this could point toward a simple, natural supplement to help manage inflammation and heart-disease risk in dialysis patients.
What could go wrong
This is a small, early-stage trial with only 56 participants. The supplement may not produce meaningful improvements, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Sep 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female patients older than 18. * Patients undergoing regular HD for at least 3 months prior to enrollment. * Not participate in any other clinical trials. * Physically stable. Exclusion Criteria: * Patients taking antioxidant supplements prior to the study's two-month time frame. * Patients with autoimmune, liver, cancer diseases and acquired immunodeficiency syndrome (AIDS). * Sensitivity to pumpkin seed oil. * Patients taking warfarin. * History of drug or alcohol abuse. * Pregnant or breastfeeding women and women with the possibility of getting pregnant. * Smokers.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodialysis patients

Contacts and locations

Locations

  • Adult Nephrology and Dialysis Unit, Ain Shams University Hospital, Cairo, Egypt.

    Cairo, 11766, Egypt

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