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Can pedaling during dialysis make red blood cells more flexible?

NCT ID NCT06575634

Symptom relief Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are testing whether supervised exercise can change how red blood cells behave in people with end-stage kidney disease who receive hemodialysis. About 180 participants will cycle during dialysis sessions three times a week for six months, then exercise at home for three months. The study measures red blood cell deformability and clumping, along with fitness and oxygen use, to see if exercise affects blood flow properties.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised exercise training, including cycling during dialysis and at home
What this could lead to
If exercise improves how red blood cells flow, it could offer a low-cost way to help people on dialysis feel better and reduce heart strain.
What could go wrong
This is a small, single-center study, and any changes in blood cell behavior may not translate into real health benefits. Exercise during dialysis carries risks like low blood pressure or fatigue, and some participants may not stick with the program.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Started

Aug 2022

Expected to finish

Jul 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Receiving hemodialysis and medication at least for 6 weeks * Kt/V score \> 1.2 Exclusion Criteria: * Under 20 years-old * Hyperkalemia occurs within 3 month * Having orthopedic or muscular diseases * Other concerned medical, psychological or physiological diseases * Pregnancy * Other exercise contraindications

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Conditions

The condition(s) this trial relates to.

dialysis disequilibrium syndrome end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodialysis complication

Contacts and locations

Locations

  • Chang Gung University

    Taoyuan, Taoyuan, 333, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.