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Simple massage and stretching tested for dialysis cramps

NCT ID NCT06759376

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 21, 2026 · Updated 5 times

Summary

This study tested whether a 10-minute vibration massage or static stretching exercise could reduce the severity and duration of muscle cramps that often occur during hemodialysis. Thirty adults with chronic kidney disease on dialysis were randomly assigned to receive vibration massage, stretching, or usual care. Researchers also measured salivary cortisol levels to see if these interventions lowered stress. The goal is to find a safe, non-drug way to manage these painful cramps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
vibration massage and static stretching exercise
What this could lead to
If effective, these simple techniques could offer drug-free relief from painful muscle cramps during dialysis and help reduce stress.
What could go wrong
This is a very small, completed trial with only 30 participants, so results may not apply to everyone. The interventions are short-term and may not work for all cramp types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Nov 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years of age and over, conscious, Turkish speaking and understanding, accepting the research, * Patients with normal body mass index (18.5-24.9) \[Since body mass can affect the distribution of vibration and cortisol level, it was planned to include patients with normal body mass index in the sample\]. * Patients with intradialytic muscle cramp in the lower extremities will be included \[Although intradialytic cramp often occurs in the lower extremities, vibration massage and static stretching exercise will be applied to the same muscle group (gastrocnemius and soleus muscles) in the lower extremities to keep the variables under control\]. Exclusion Criteria: * Intradialytic muscle cramps in the upper extremity, * Intradialytic muscle cramps, those with incomplete tissue integrity in the region and thrombophlebitis, hematoma, etc. \[In order for vibration massage to be performed, individuals must have skin integrity and normal blood characteristics.\] * Those with foot deformation, * Those who use anti-inflammatory, analgesic drugs and those who additionally use adjuvant therapy (antidepressants, anticonvulsants, muscle relaxants, etc.) up to 4 hours before the HD session, as intradialytic muscle cramps and their duration may be affected, * Those who are taking routine cortisone treatment and medications with hormonal effects (oral contraceptives, steroid-containing bronchodilators, etc.) so that the salivary cortisol test is not affected. --Alcohol users, * Hypoglycemic patients, * Patients with psychiatric diagnosis and those using medication related to this diagnosis, * Patients with mouth ulcers, inflammation, etc. * Patients who ate or drank anything other than water, chewed gum, or consumed foods or beverages containing citric acid 15 minutes before intradialytic muscle cramping, * Patients who use high doses of biotin (\>5 mg/day) and whose last biotin treatment has not passed 8 hours.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Private Anatolian Dialysis Center

    Eskişehir, Turkiye, Turkey (Türkiye)

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