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Kidney transplant study compares immune effects of two common drugs

NCT ID NCT02894606

First seen Jun 09, 2026 · Last updated Jun 22, 2026 · Updated 3 times

Summary

This study looked at 49 kidney transplant patients to see how two different induction therapies—thymoglobulin and basiliximab—affect B cells, a type of immune cell. Researchers compared the B cell profiles between the two groups and with data from patients who had chronic antibody-mediated rejection. The goal was to better understand how these drugs influence the immune system after transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Brest

    Brest, 29200, France

  • Tours University Hospital

    Tours, 37000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Thymoglobulin and basiliximab (induction therapies given before kidney transplant to prevent rejection)

What this could lead to

If successful, this could help doctors choose the best induction therapy for kidney transplant patients and reduce the risk of chronic rejection.

What could go wrong

This is a small, observational study that does not test a new treatment. It only looks at immune cell changes, so it may not lead to direct improvements in patient care.

Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.