University Hospital, Brest

This study compares two newer blood thinners (apixaban and rivaroxaban) to daily low-dose aspirin for preventing blood clots in people with JAK2-positive myeloproliferative neoplasms (blood cancers like polycythemia vera). About 1,300 high-risk patients will be followed to see wh…

This study tests whether a minimally invasive procedure using a medical glue (cyanoacrylate) can prevent chronic subdural hematoma—a collection of blood on the brain—from returning after standard care. About 550 adults with a hematoma larger than 10 mm will be randomly assigned t…

This study is testing a new type of PET scan to see if it can tell the difference between leftover cancer and swelling caused by radiation in people treated for head and neck cancer. About 180 adults who finished radiation therapy will get this special scan 3 months after treatme…

This study tests if naloxegol, a drug that blocks opioid side effects in the gut, can prevent constipation and pneumonia in brain-injured patients in the ICU. About 370 adults on ventilators and opioids will receive either naloxegol or a placebo. The goal is to see if early treat…

This study tests a program called PREVENTURE, designed to help vulnerable teenagers aged 14-17 reduce risky drinking and substance use. Participants are identified through a personality questionnaire and randomly assigned to either the program plus usual care, or usual care alone…

This study tests whether a nasal spray made from electrodialyzed seawater can shorten the time babies (1 month to under 1 year) have symptoms of acute bronchiolitis, compared to standard saline spray. About 458 infants with their first, mild-to-moderate episode will be randomly a…

This study tests if a capsaicin 8% skin patch (made from chili peppers) can reduce chronic nerve pain in teenagers aged 12 to 17 who have had pain for over 3 months after surgery or an injury. About 46 teens will either get the real patch or a dummy patch. The main goal is to see…

This study tests whether wearing Boarding Ring glasses can help people with vestibular neuritis (a sudden, severe dizziness caused by inner ear nerve inflammation) recover their sense of balance more quickly. About 51 adults will wear the glasses and be monitored for 7 days. The …

This study looks at whether personalized support from a sports and health professional can help people with heart failure stay physically active for a full year after completing a cardiac rehab program. About 90 adults with stable heart failure will either receive this tailored f…

This study looks at whether ultrasound images of the temporal and axillary arteries can help predict when giant cell arteritis (GCA) will flare up again. GCA is a condition that causes inflammation in medium and large blood vessels. Researchers will follow 100 adults with GCA to …

This study looks at how the CFTR gene is organized and controlled in cells from the epididymis, a part of the male reproductive system. Researchers will collect leftover tissue from 20 men already scheduled for surgery, including those with cystic fibrosis or a condition causing …

This study is not testing a new treatment. Instead, it will combine health information from 20,000 people across 14 European research groups who have had blood clots (venous thromboembolism). The goal is to create a single, large database to help researchers better predict who is…

This study aims to understand what causes a sensitive scalp by looking at genes and skin structure. Researchers will compare 40 women—some with a sensitive scalp and some without—using small skin samples. The goal is to find biological differences that explain why certain people …

This study looks at whether training paramedics with simulations (role-playing) can make patients with a newly found brain tumor feel more satisfied with their hospital care. About 250 adults will answer a questionnaire after their hospital stay. The goal is to see if this traini…

This study looks at how preterm and full-term babies get used to sounds and lights (called habituation). Researchers will compare 70 infants to see if preterm babies have different responses. The goal is to find early signs of brain development issues so that help can be given so…

This study looks at whether young people (ages 15-25) with early signs of psychosis have trouble recognizing themselves or telling themselves apart from others. Researchers will compare them to healthy volunteers using a special mirror task. The goal is to better understand these…

This study looks at whether a special parenting program can lower stress for parents with alcohol use disorders and their children aged 4 to 12. About 90 families will take part. Researchers will measure stress levels before and after the program to see if it helps.

This study follows 3,400 people who have had a blood clot (venous thromboembolism) to see how often clots return over time. It focuses on two groups: patients under 50 years old and cancer patients of any age. Researchers will track recurrences, bleeding, and other complications …

This study aims to find genetic factors that may cause repeated miscarriages (three or more in early pregnancy) or unexplained fetal death later in pregnancy. Researchers will compare DNA from 200 couples who have experienced these losses with DNA from couples who have not. The g…

This study tests a French version of a questionnaire that measures the burden on people caring for a loved one with COPD. Researchers will ask 224 caregivers to fill out the questionnaire and compare it with other standard surveys. The goal is to provide a reliable tool to identi…

This study follows 217 people aged 15-30 after their first psychotic episode to see if speech patterns and blood markers can predict whether they will develop bipolar disorder or schizophrenia. Researchers will record interviews and analyze language using machine learning. The go…

This study aims to better understand rare forms of inflammatory arthritis, including those linked to autoimmune diseases or cancer immunotherapy. Researchers will analyze joint tissue samples from 100 adults to compare immune cell patterns with common arthritis types. The goal is…

This study is for cancer patients receiving immune checkpoint inhibitors (a type of immunotherapy). Researchers want to see if blood tests can predict who will develop side effects from this treatment. About 200 adults will give blood samples during their regular check-ups. The g…