University Hospital, Brest
Clinical trials sponsored by University Hospital, Brest, explained in plain language.
-
Before or after meals? study tests best time for insulin in type 1 diabetes
Disease control CompletedThis study looked at 22 adults with type 1 diabetes who use an insulin pump. It compared taking a fast-acting insulin (insulin aspart) just before a meal versus right after a meal. The goal was to see which timing leads to better blood sugar control over 14 days. The results help…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
-
Smart fluid dosing may reduce organ damage in septic shock
Disease control CompletedThis study tested a personalized approach to giving fluids to people with septic shock, a life-threatening condition. Instead of a one-size-fits-all method, doctors used a 'mini-fluid challenge' to tailor fluid amounts to each patient's needs. The goal was to reduce organ failure…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated May 01, 2026 15:56 UTC
-
Hidden clues in negative HPV tests could spot cancer earlier
Diagnosis CompletedThis study looked at 45 patients whose HPV tests came back negative but had a late signal in the lab results. Researchers wanted to see if this signal could actually mean there are early cell changes (lesions) that might lead to cervical cancer. By comparing different lab methods…
Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated May 01, 2026 15:59 UTC
-
New scan could spot dangerous lung clots faster and safer
Diagnosis CompletedThis study tested whether a special PET/CT scan (V/Q PET/CT) can accurately diagnose pulmonary embolism (a blood clot in the lungs) compared to the standard CT scan. About 100 adults with suspected first-time clots took part. The goal was to see if the new scan is as good or bett…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Apr 30, 2026 15:50 UTC
-
New CT scan technique could improve blood clot detection in lungs
Diagnosis CompletedThis study tested a new CT scan method to see if it can find blood clots in the lungs as well as the standard SPECT scan. The new method uses a single CT scan to create a map of blood flow, potentially giving doctors both the clot location and its effect on lung function. 30 adul…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Apr 30, 2026 15:49 UTC
-
New french tool aims to spot hidden depression in Doctor's offices
Diagnosis CompletedThis study tested whether a French translation of the HSCL25 questionnaire can accurately help general practitioners diagnose depression. Over 1,100 adults visiting their primary care doctor took part. Researchers compared the HSCL25 results with another standard questionnaire to…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Apr 30, 2026 15:49 UTC
-
Can a pill stop excessive sweating? new trial results
Symptom relief CompletedThis study tested the drug oxybutynin to see if it can reduce excessive sweating (hyperhidrosis). 62 adults with severe sweating took either the drug or a placebo. Researchers measured how much sweating improved and how it affected daily life, and also checked for side effects.
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated May 01, 2026 16:01 UTC
-
Breathing workout boosts rehab for COPD patients?
Symptom relief CompletedThis study looked at whether adding special breathing muscle exercises to a standard 3-week pulmonary rehab program helps people with COPD feel less short of breath. 38 patients took part. The goal was to see if the combined approach works better than rehab alone for improving br…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
-
Shocking muscles or pedaling: which helps COPD patients breathe easier?
Symptom relief CompletedThis study looked at two different exercise methods for people with severe COPD: using electrical stimulation to activate leg muscles versus pedaling a stationary bike. Both were part of a 3-4 week hospital rehab program. The goal was to see which approach better improves leg str…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Apr 29, 2026 15:15 UTC
-
Can a simple text message save lives? small study tests SMS for suicide prevention
Knowledge-focused CompletedThis study looked at whether sending text messages to caregivers of people who survived a suicide attempt is a practical way to check on them. Fifteen adults who were hospitalized after a suicide attempt and their caregivers took part. The goal was to see if patients and caregive…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
-
Weight-Loss surgery may change how blood thinners work
Knowledge-focused CompletedThis study looked at how the blood thinner rivaroxaban acts in people with severe obesity and in those who had weight-loss surgery (gastric bypass or sleeve gastrectomy). 67 participants took rivaroxaban for 8 days, and researchers measured drug levels and blood clotting. The goa…
Phase: PHASE1 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
-
Researchers test how your body shape affects shoulder stability
Knowledge-focused CompletedThis study measured how body size and physical activity level affect a shoulder stability test called the CKCUEST. 82 healthy adults aged 18-25 did a push-up style test where they touched one hand to the other as many times as possible in 15 seconds. The goal was to see if factor…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
-
Brain's balance tricks may predict ACL tears in young handball stars
Knowledge-focused CompletedThis study looked at how well the brain can adjust balance signals (proprioception) in young handball players. 41 athletes aged 15-25 did jumping and sidestep cutting tests. The goal was to see if poor balance adjustment is linked to higher knee injury risk. Results may help desi…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
-
Stepping up: new test may track COPD rehab success
Knowledge-focused CompletedThis study looked at whether a simple six-minute stepper test can show improvements in exercise tolerance for people with COPD after a 3-week pulmonary rehabilitation program. Researchers measured the number of steps taken before and after rehab in 72 patients. The goal was to se…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
-
Rocker shoes put to the test for diabetic nerve patients
Knowledge-focused CompletedThis study looked at whether rocker sole shoes, often prescribed for foot problems, cause balance issues in people with type 2 diabetes and nerve damage (neuropathy). Twenty-five adults who could walk without help stood still for 55 seconds in both regular and rocker shoes while …
Phase: PHASE4 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
-
Hidden danger in COPD Flare-Ups: blood clots found more often than expected
Knowledge-focused CompletedThis study looked at 750 people hospitalized for a COPD flare-up to find out how many also had a pulmonary embolism (a blood clot in the lung). Doctors used a standard set of tests, including a blood test and special scans, to check for clots. Participants were followed for 3 mon…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC
-
Full bladder may change uterus angle, easing IUD insertion
Knowledge-focused CompletedThis study looked at 200 women who have had at least one child to see how a full versus empty bladder changes the angle of the uterus. Researchers used ultrasound to measure the uterus before and after urination. The goal is to find ways to make IUD insertion less painful and eas…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC