Can smarter fluid dosing save lives in septic shock?
NCT ID NCT03461900
First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 30 times
Summary
This study tested a personalized approach to giving fluids to people with septic shock, using small fluid challenges to guide treatment. The goal was to reduce organ failure by avoiding both too little and too much fluid. Over 500 adults in intensive care took part, and the approach was compared to standard care. The main outcome measured was change in organ failure over five days.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Angers university hospital
Angers, France
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Besançon university hospital
Besançon, France
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Brest university hospital
Brest, 29200, France
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Brest university hospital
Brest, France
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Chartres Hospital
Chartres, 28000, France
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Clermont Ferrand university hospital
Clermont-Ferrand, France
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George Pompidou university hospital (APHP)
Paris, France
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Hôpital privé de l'ouest parisen
Trappes, 78190, France
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Kremlin Bicêtre university hospital (APHP)
Paris, France
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Le Mans hospital
Le Mans, France
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Marseille university horpital
Marseille, France
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Morlaix hospital
Morlaix, France
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Nantes university hospital
Nantes, France
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Nîmes university hospital
Nîmes, 30029, France
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Poitiers university hospital
Poitiers, France
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Rouen university hospital
Rouen, France
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Toulon hospital
Toulon, France
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Tours university hospital
Tours, France
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.