Could a week of breathing support before lung surgery cut risks in half?

NCT ID NCT01685580

Completed Disease control Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

First seen Jan 07, 2026 · Last updated Jun 19, 2026 · Updated 24 times

Summary

This study tested whether using a non-invasive ventilation machine for at least 7 days before lung cancer surgery could reduce lung and heart complications. The trial included 300 patients with lung cancer who also had breathing problems, obesity, or heart failure. The goal was to see if this approach could halve the rate of serious postoperative issues.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

CHI Créteil

Créteil, 94010, France
CHRU de Brest - Hôpital Morvan

Brest, 29609, France
CHU Angers

Angers, 49933, France
CHU Limoges

Limoges, 87042, France
CHU Saint-Etienne

Saint-Etienne, 42055, France
CHU de Rouen

Rouen, France, 76031, France
Centre Hospitalier Victor Dupouy

Argenteuil, France, 95100, France
Centre Hospitalier du Pays d'Aix

Aix-en-Provence, France, 13616, France
Clinqiue du Grand Large

Brest, France, 29200, France
Hospital, Pasteur

Nice, 06000, France
Hôpital Nord Ouest Villefranche Sur Saône

Villefranche-sur-Saône, France, 69655, France
Hôpital Pontchaillou

Rennes, France, 35033, France
Inter Army Hospital

Clamart, 92141, France
Inter Army Hospital, Clermont-Tonnerre

Brest, 29609, France
Inter Army Hospital, Saint-Anne

Toulon, 83041, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-invasive ventilation device (VPAP ST)

What this could lead to

If it works, this could make lung cancer surgery safer for patients with breathing or heart problems by reducing serious complications.

What could go wrong

This is a completed trial, but results may not apply to all patients. The technique is not a treatment for cancer itself, only a way to lower surgical risks.

Conditions

The condition(s) this trial relates to.

lung cancer non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SURGERY FOR PRIMARY LUNG CANCER