New hope for water itch: drug showdown targets rare blood cancer side effect
NCT ID NCT03808805
First seen Jan 10, 2026 · Last updated May 23, 2026 · Updated 19 times
Summary
This study tested two oral drugs, aprepitant and hydroxyzine, to see which better reduces severe itching triggered by water in people with myeloproliferative neoplasms (a type of blood cancer). 63 participants who had persistent itching rated 5 or higher on a 10-point scale were randomly assigned to one of the drugs. The goal was to lower itching to 3 or below. The trial is complete and aims to find a more effective way to manage this uncomfortable symptom.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU de Brest - Hôpital Morvan
Brest, Brest Cedex, 29609, France
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CHU Grenoble Alpes
Grenoble, 38043, France
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CHU d'Angers
Angers, 49933, France
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CHU de Caen
Caen, 14033, France
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CHU de Nantes
Nantes, 44093, France
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Centre Hospitalier de Cornouaille
Quimper, Quimper, 29107, France
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Centre Hospitalier de Douarnenez
Douarnenez, 29171, France
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Centre Hospitalier des Pays de Morlaix
Morlaix, 29672, France
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Centre Léon Bérard
Lyon, 69373, France
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Hôpital Pontchaillou
Rennes, France
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Hôpital Yves Le Foll
Saint-Brieuc, 22027, France
Conditions
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