Engineered blood vessel could simplify dialysis for kidney patients
NCT ID NCT03183245
First seen Nov 20, 2025 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This phase 3 trial tested a lab-grown blood vessel (Human Acellular Vessel, or HAV) against the standard surgically created fistula in 242 people with end-stage kidney disease on hemodialysis. The goal was to see which option works better for providing reliable access to filter blood. The study measured how well each access type functioned at 6 months and how long it lasted without being abandoned.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alliance Research
Laguna Hills, California, 92653, United States
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Arizona Kidney Disease and Hypertension Center (AKDHC)
Phoenix, Arizona, 85012, United States
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Balboa Nephrology
San Diego, California, 92123, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Coastal Vascular & Interventional, PLLC
Pensacola, Florida, 32503, United States
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Decatur Memorial Hospital
Decatur, Illinois, 62526, United States
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Denver Health Medical Center
Denver, Colorado, 80204, United States
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Grady Memorial Hospital
Atlanta, Georgia, 30303, United States
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Huntington Hospital
Pasadena, California, 91105, United States
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Kaiser Permanente Sunnsyide
Portland, Oregon, 97015, United States
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Kidney Care & Transplant Services of New England
West Springfield, Massachusetts, 01089, United States
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Memorial Healthcare System
Pembroke Pines, Florida, 33021, United States
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Mills Peninsula Hospital
San Mateo, California, 94401, United States
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Olive View- UCLA Medical Center
Sylmar, California, 91342, United States
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Overlook Medical Center
Summit, New Jersey, 07901, United States
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Rutgers University
Newark, New Jersey, 07103, United States
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South Plains Surgery Center
Lubbock, Texas, 79416, United States
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Surgical Specialists of Charlotte
Charlotte, North Carolina, 28207, United States
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Tampa General Hospital
Tampa, Florida, 33606, United States
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The Regional Medical Center
Orangeburg, South Carolina, 29118, United States
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The Vascular Experts
Darien, Connecticut, 06820, United States
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UC Davis
Sacramento, California, 95817, United States
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United Surgical Associates
Lexington, Kentucky, 40504, United States
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University of Arizona
Tucson, Arizona, 85724, United States
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University of CA, San Diego - LaJolla VA Hospital
La Jolla, California, 92161, United States
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University of California San Diego, Jacobs Medical Center
La Jolla, California, 92103, United States
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University of California, Irvine
Irvine, California, 92868, United States
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University of Southern California
Los Angeles, California, 90033, United States
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University of Tennessee Knoxville
Knoxville, Tennessee, 37920, United States
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VA Long Beach Healthcare System
Long Beach, California, 90822, United States
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VA Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Human Acellular Vessel (HAV)
What this could lead to
If it works, this could provide a reliable, ready-to-use option for dialysis access, reducing the need for multiple surgeries.
What could go wrong
This is a completed phase 3 trial, but the HAV may not work as well as a natural fistula for everyone, and there are risks of infection or blockage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.