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Ultrasound could help dialysis patients hit the right fluid balance

NCT ID NCT07659197

Knowledge-focused Sponsor: Fundación Senefro Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a special ultrasound check (called VExUS) can help doctors set the ideal dry weight for people on hemodialysis. The idea is that by spotting hidden fluid buildup, doctors can safely remove more fluid during dialysis to better control blood pressure. The study included 72 adults who had been on dialysis for at least three months. Researchers compared those with signs of fluid congestion (who got extra fluid removal) to those without (who stayed on their usual plan).

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive way to set the right fluid removal target during dialysis, potentially improving blood pressure control.
What could go wrong
This is a small, completed observational study (72 people) without a control group, so results may not apply broadly. The ultrasound technique may not reliably predict who can safely tolerate more fluid removal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

72 people

The number who actually took part.

Started

Jan 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years of age who are currently on hemodialysis (more than 90 days since the start of the program) * A schedule of three days per week at the centers included in the study * Signed informed consent Exclusion Criteria: * Clinical signs and symptoms of volume overload * Patients with liver disease (liver cirrhosis, steatosis, portal vein thrombosis) * Severe tricuspid regurgitation * Inability to hold one's breath * Obesity

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Conditions

The condition(s) this trial relates to.

end stage renal failure hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodialysis Hypertension (HTN)

Contacts and locations

Locations

  • Hospital Universitario Infanta Leonor

    Madrid, Madrid, 28055, Spain

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