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Cooling dialysis fluid may fight fatigue after treatment

NCT ID NCT07071376

Symptom relief Sponsor: Baskent University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether lowering the temperature of the dialysis fluid from 36.5°C to 36°C could reduce the tiredness patients often feel after dialysis. Fifty-seven adults on maintenance hemodialysis received three sessions of 'cold dialysis' over one week. Researchers measured fatigue and thermal comfort to see if this simple change helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cold dialysis (dialysate temperature lowered from 36.5°C to 36°C)
What this could lead to
If it works, this simple temperature change could offer a low-cost way to ease fatigue after dialysis, improving daily life for patients.
What could go wrong
This is a small, completed study with only 57 participants, so results may not apply to everyone. The temperature change is minor, and fatigue is subjective, so benefits might be modest or not reproducible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

57 people

The number who actually took part.

Started

May 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who agreed to participate in the study * Age 18 and over * Having been on hemodialysis for at least 6 months * Having hemodialysis 3 times a week * Having a post-dialysis fatigue score ≥28. Exclusion Criteria: * Having an active infection * Having a body temperature above 37.5°C * Having serious cardiovascular diseases (e.g., uncontrolled hypertension, congestive heart failure) * Having a history of acute complications during dialysis * Having a history of severe hypotension * Patients whose dialysis treatment was interrupted

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Conditions

The condition(s) this trial relates to.

dialysis disequilibrium syndrome end stage renal failure wild type ABeta2M amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dialysis related complication

Contacts and locations

Locations

  • Baskent University

    Ankara, Türkiye, 109861, Turkey (Türkiye)

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