COLORECTAL CANCER

This study tested a cancer vaccine called ETBX-011 in 43 people with advanced colorectal, lung, breast, or prostate cancers that make a protein called CEA. The vaccine uses a modified virus to teach the immune system to find and attack CEA-making cancer cells. The main goals were…

This early-phase study tested a new drug called CUE-102 in 42 adults with advanced colorectal, gastric, pancreatic, or ovarian cancers that had stopped responding to standard treatments. Participants had a specific genetic marker (HLA-A*0201) and their tumors produced a protein c…

This study tested a new computer-based tool to help doctors adjust chemotherapy doses for people with cancers of the digestive system (like colorectal or stomach cancer). The goal was to reduce unplanned delays in treatment while keeping the dose strong enough to fight the cancer…

This early-phase study tested a new treatment called VE800, made from live bacteria, combined with the immunotherapy drug nivolumab in 56 people with advanced or metastatic cancers like melanoma, stomach, and colorectal cancer. The main goals were to check safety and see if tumor…

This study tested a new drug combination (MK-4280A) in 441 people with advanced colorectal cancer that had spread and stopped responding to prior treatments. The goal was to see if the new treatment helped people live longer compared to standard therapies. The approach uses two d…

This study tested a device called Colovac 2 in 24 people having surgery for colon cancer. The device is placed inside the body to temporarily protect the new connection made between the remaining parts of the bowel. The goal was to see if the device stays in place and works safel…

This early-phase trial tested a new immunotherapy called ELI-002 in 25 people with KRAS-mutated pancreatic, colorectal, lung, ovarian, or bile duct cancers that had minimal residual disease after standard treatment. The goal was to see if the treatment is safe and can reduce canc…

This early-phase study tested a new drug called TPST-1495, alone or with another drug (pembrolizumab), in 89 people with advanced solid tumors (like colorectal, lung, or head and neck cancer) that had stopped responding to standard treatments. The main goal was to find the safest…

This study tested a new drug combination (MK-4280A) against standard treatments in 94 Chinese adults with advanced colorectal cancer that had spread and no longer responded to prior therapy. The main goal was to see if the new combo helped people live longer. The approach uses tw…

This early-stage study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of a chemotherapy agent, given through an IV, and the m…

This study tested a combination of three drugs (encorafenib, binimetinib, and cetuximab) given before surgery to people with a specific genetic type of colorectal cancer (BRAF V600E). Only 2 people took part. The main goal was to see how much the tumor shrank after treatment and …

This early-phase study tested the safety and best dose of two drugs—regorafenib and nivolumab—given together to people with advanced colorectal cancer that has not responded to standard treatments. The cancer type studied is mismatch repair proficient, meaning it does not have a …

This study looked at whether a combination of daily vitamin D, aspirin, exercise, and a low-fat diet could reduce the chance of colorectal cancer returning in people who had already been treated. Sixteen participants with no visible cancer but with signs of leftover disease in th…

This study tested a combination of two drugs, lenvatinib and pembrolizumab, in 611 people with advanced solid tumors including breast, ovarian, stomach, colorectal, brain, bile duct, and pancreatic cancers that had stopped responding to standard treatments. The goal was to see if…

This study tested a drug called prolgolimab, which helps the immune system fight cancer, in 30 people with a specific type of colorectal cancer (MSI/dMMR) that had not spread. Participants received the drug for 6 months before surgery. The main goal was to see if the cancer compl…

This study tested a new drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. The study was completed, …

This study tested a drug called revumenib in 42 adults with colorectal cancer or other solid tumors that had spread or come back after at least one prior treatment. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors or slow their gro…

This early-phase study tested the safety of a new drug called GDC-1971 when given with either osimertinib (for lung cancer) or cetuximab (for colorectal cancer). It involved 10 adults with advanced cancer that had spread or couldn't be removed. The main goal was to check for side…

This study tested a device called Colovac+ in 27 adults having colorectal cancer surgery. The device is placed inside the bowel to protect the surgical connection and keep stool away while it heals. The goal was to see if it could help patients avoid a temporary colostomy bag and…

This study tested a treatment for colorectal cancer that has spread to the liver. A small pump placed under the skin delivers chemotherapy directly to the liver over two weeks. The goal was to see if this approach could shrink liver tumors. 24 adults took part, and the study is n…

This study tested a new drug called SAR444245 combined with other cancer treatments in 138 adults with advanced gastrointestinal cancers, including esophageal, stomach, liver, and colorectal cancer. The goal was to see if the combination could shrink tumors. The study is complete…

This study looked at whether adding the drug celecoxib (often used for arthritis) to standard chemotherapy helps prevent colon cancer from coming back after surgery. About 2,500 patients with stage III colon cancer took part. They received either 6 or 12 rounds of chemo, plus eit…

This study tested whether adding cetuximab (a targeted antibody) to a strong chemotherapy cocktail (FOLFIRINOX) could shrink tumors better in people with metastatic colorectal cancer that had spread and could not be removed by surgery. 42 patients received the combination as thei…

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced cancers like stomach, lung, or liver cancer that had stopped responding to treatment. The goal was to find a safe dose and see if the drugs could shrink …

This early-phase study tested whether a heated chemotherapy drug called raltitrexed is safe and tolerable for people with colorectal cancer. Thirty patients received the treatment directly into their abdomen during surgery. Researchers monitored side effects, drug levels in the b…

This study tested a combination of three drugs (nivolumab, trametinib, and ipilimumab) in 325 people with advanced colorectal cancer that had spread and was no longer responding to standard treatments. The goal was to see if these drugs could shrink tumors or slow the cancer's gr…

This early-phase study tested an experimental drug called SHR-A1811 in 101 people with advanced stomach or colorectal cancers that have a specific protein (HER2). The main goals were to check safety, find the right dose, and see if the drug can shrink tumors. Participants had can…

This early-phase study tested the safety of combining the immunotherapy drug pembrolizumab with precise radiation (SBRT) to the liver in 15 adults with colorectal cancer that had spread only to the liver. The goal was to see if this approach could prevent the cancer from returnin…

This study tested whether more intense chemotherapy could help people with colorectal cancer that has spread to the liver and cannot be fully removed by surgery. 124 adults received either standard two-drug chemo or one of three stronger three-drug combinations. The goal was to s…

This early-phase study tested a personalized vaccine made from yeast that is designed to teach the immune system to recognize and attack leftover cancer cells. It included 5 adults with different cancers who had already completed treatment aimed at curing their disease. The goal …

This early-phase study tested a new daily pill called JAB-3312 in 40 adults with advanced solid tumors (like lung, colorectal, or breast cancer) that had stopped responding to standard treatments. The main goals were to find the safest dose and check for side effects. Researchers…

This study looked at whether a structured physical activity program, along with health education materials, could help prevent colon cancer from returning in people who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. A total of 889 patients took par…

This study looked at whether a Medtronic pump and Codman catheter could safely deliver chemotherapy directly to the liver in 35 people with colorectal cancer that spread to the liver or bile duct cancer. The main goal was to check safety, like liver side effects and need for sten…

This study tested the drug tislelizumab given before surgery in 33 people with early-stage (stage II-III) colorectal cancer that has specific genetic changes (MSI-H or dMMR). The goal was to see if the drug could shrink or eliminate the tumor before surgical removal. The main mea…

This study tested the drug nivolumab in 35 people with a certain kind of advanced colorectal cancer that has not responded to standard treatments. The goal was to see if the drug could stop the cancer from growing for at least 27 weeks. The trial is complete, and results help und…

This study tested an experimental drug called BMS-813160, given alone or with chemotherapy and/or the immunotherapy nivolumab, in 332 people with advanced colorectal or pancreatic cancer. The main goals were to check safety and side effects, and to see if the drug combination cou…

This study tested a drug called axitinib against a placebo in 52 people with advanced colorectal cancer that had spread to the liver and stopped responding to at least two chemotherapy treatments. The goal was to see if axitinib could help control the cancer and to test a new ult…

This early-phase study tested whether adding two drugs (romidepsin and 5-azacitidine) to an immunotherapy (MK-3475) could help people with a specific type of advanced colorectal cancer called microsatellite stable (MSS). The study included 27 adults whose cancer had already sprea…

This early-phase study tested a combination of two drugs, cabozantinib and TAS-102, in 15 people with metastatic colorectal cancer that had stopped responding to standard treatments. The main goal was to find the safest dose and check for side effects. The study is complete and h…

This study tested whether a high-protein drink with added arginine could reduce complications after colorectal surgery in 44 malnourished adults. Participants received either the arginine-enriched drink or a standard high-protein drink before and after surgery. Researchers tracke…

This early-phase study tested a drug called gevokizumab alongside standard cancer treatments in 167 adults with advanced colorectal, stomach, or kidney cancer. The goal was to find a safe dose and see if the combination helps control tumor growth. While not a cure, it aims to imp…

This study tested a chemotherapy pill (TAS-102) combined with targeted radiation for people with colorectal cancer that has spread to the liver. The goal was to find the safest dose and see how well the combination controls tumor growth. About 52 adults with 1 to 4 liver tumors t…

This study looked at whether giving nutrition through a small vein in the arm (peripheral parenteral nutrition) helps patients recover better after colorectal surgery. The trial included 200 adults who had surgery for conditions like colorectal cancer or inflammatory bowel diseas…

This study tested a new PET imaging agent called [18F]FAPI-74 in 109 people with gastrointestinal cancers, including liver, bile duct, stomach, pancreas, and colorectal cancers. The goal was to see if the scan could accurately find cancer cells by targeting a protein called FAP. …

This study tested whether ultrasound can detect nerve damage caused by the chemotherapy drug oxaliplatin in people with gastrointestinal cancer. Twenty participants who had or were receiving oxaliplatin and had symptoms of nerve damage were enrolled. Researchers compared ultrasou…

This study tested whether using a camera capsule (pill) as a first step in bowel cancer screening could encourage more people to get screened and find more polyps or cancers. Over 2,000 participants from the Danish screening program took part. The goal was to see if the capsule c…

This study checked if specially trained dogs can detect breast, lung, prostate, or colorectal cancer just by smelling a person's breath. Over 1,300 adults gave breath samples by breathing into a mask. The dogs then sniffed the masks and said whether they thought cancer was presen…

This study tested a new radioactive imaging agent called 68Ga-NODAGA-SNA009 in 12 people with colorectal cancer. The goal was to see if it is safe and how it spreads through the body and tumors. Researchers measured radiation doses and checked if the agent can help spot cancer ce…

This study looked at over 5,000 people aged 45-75 who were overdue for colorectal cancer screening. Participants received either a FIT or Cologuard test in the mail to complete at home. The goal was to see which test more people actually finished, helping improve screening rates …

This study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45 to 85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths com…

This study tested whether a new at-home stool DNA test (Cologuard) could help more Alaska Native people get screened for colorectal cancer, which is very common in this group. Over 2,000 adults who were due for screening were randomly assigned to receive the test with extra suppo…

This study tested a program to increase colorectal cancer screening among adults aged 50-74 in 12 Appalachian counties. The program worked with clinics, doctors, and patients to encourage screening. Over 5,400 people took part, and the goal was to see if screening rates improved.

This study tested whether a one-time colonoscopy or yearly stool tests are better at finding early signs of colorectal cancer in healthy people aged 50 to 69. Over 4,900 participants were randomly assigned to one of the two screening methods. The goal was to see which approach de…

This study tested whether mailing a simple stool test (FIT) to people's homes could increase colorectal cancer screening rates. Over 4,300 adults aged 45-75 who were at average risk took part. The goal was to make screening easier and catch cancer earlier, especially in underserv…

This study looked at different ways to encourage people aged 50 to 75 to get screened for colorectal cancer. Participants were from a health center and were not up to date with screening. The study compared usual care, outreach (like mail or phone reminders), and inreach (reminde…

This study tested a community-based program to encourage colorectal cancer screening in rural China. Over 20,000 adults aged 45-70 took part. The goal was to increase the number of people who complete a colonoscopy after initial screening, which can catch cancer early and improve…

This study looked at 60 spouses of people who had colorectal cancer. The goal was to see if giving them extra education and support would make them more likely to complete a simple at-home screening test (FIT kit) for colorectal cancer. The researchers compared two groups to find…

This study looked at whether taking magnesium supplements could reduce the risk of colorectal cancer in people with a specific genetic makeup. Researchers gave 250 participants either magnesium or a placebo for 12 weeks and measured changes in colon tissue markers linked to cance…

This study tested a mobile app called PainPac designed to help people with colorectal cancer manage pain. Researchers wanted to see if it was practical and acceptable for patients to use. 62 adults took part, and the app provided coping strategies and tracked pain to improve care…

This study looked at which of two oral chemotherapy drugs (Xeloda or UFT with folinic acid) people with advanced colorectal cancer prefer. After trying both treatments in a crossover design, patients chose their favorite. The study also checked how safe each drug was. 89 adults w…

This study looked at whether N-Acetylcysteine, a common supplement, could help prevent nerve damage caused by the chemotherapy drug oxaliplatin in people with colorectal cancer. 46 patients took part. Researchers measured nerve symptoms, pain, and inflammation to see if the suppl…

This study tested whether offering free legal services to people with advanced colorectal cancer could reduce stress and financial worries. Twenty participants received personalized legal help from a nonprofit for six months. Researchers measured changes in stress, coping, and qu…

This study looked at whether teaching patients about Enhanced Recovery After Surgery (ERAS) before their operation helps them recover better. 88 adults with colorectal cancer were split into two groups: one got a special education session with a booklet, the other got standard ca…

This study looked at two ways to close the skin after colorectal cancer surgery: using metal staples or a special medical glue. The goal was to see which method leads to fewer wound infections and is more cost-effective. 304 adults who had planned colorectal surgery took part. Th…

This small pilot study tested a new mind-body program to help female colorectal and anal cancer survivors improve their sexual well-being. Six women who had finished initial cancer treatment took part in group sessions. The goal was to see if the program was acceptable and helpfu…

This study looked at whether doing special exercises before colorectal cancer surgery helps patients recover better afterward. Over 700 adults scheduled for surgery were split into two groups: one received instructions for pre-surgery training (prehabilitation), and the other got…

This study tested whether neurotropin can prevent or reduce nerve damage caused by the chemotherapy drug oxaliplatin in people with stage II or III colorectal cancer. A total of 333 adults who had surgery and were about to start chemotherapy took part. The goal was to see if neur…

This study looked at whether applying a topical diclofenac gel to the hands and feet can prevent or delay hand-foot syndrome—a painful skin reaction—in people with colorectal or gastric cancer taking the chemotherapy drug capecitabine. About 150 patients were observed at two canc…

This study looked at whether Reiki, a gentle touch therapy, can help people who had surgery for colorectal cancer feel better afterward. Researchers measured pain, anxiety, and recovery in 64 patients. The goal was to see if adding Reiki to standard care could improve comfort and…

This study tested whether personalized nursing care helps people recover better after laparoscopic surgery for colorectal cancer. 90 patients were split into two groups: one received standard care, the other got extra support like counseling before surgery, careful temperature co…

This study tested a specially designed corset to help people with colorectal cancer feel more comfortable during continuous 5-FU chemotherapy infusion. Forty patients were split into two groups: one used the corset, the other received standard care. The goal was to see if the cor…

This study tested a web-based support program for people with colorectal cancer. 24 patients were split into two groups: one got the online program plus usual care, the other got usual care alone. The goal was to see if the program helped reduce symptoms and improve quality of li…

This study tested an 11-step community program to help African Americans aged 45-75 get screened for colorectal cancer. The program provided education, risk assessment, and help with barriers like finding a doctor, transportation, and costs. 163 participants joined, and the goal …

This study looked back at the medical records of 500 people with colorectal cancer from hospitals in Xinjiang and Shandong, China. The goal was to find out how long patients typically live after diagnosis and what factors affect their survival. Researchers hope the results will h…

This study looked at how the immune drug pembrolizumab affects colorectal cancer when given before surgery. 33 patients with non-metastatic cancer received the drug along with chemotherapy or chemoradiotherapy. The goal was to measure changes in immune activity and tumor shrinkag…

This study tested whether an educational program could help people in rural areas learn more about cancer screening, especially for colorectal cancer. About 205 adults aged 45 to 74 from certain counties in New Hampshire and Vermont took part. Researchers measured changes in know…

This study looked at how drugs that interact with the body's natural cannabis-like system affect the movement of the colon. Researchers used colon tissue samples from 36 colorectal cancer patients to test these drugs in the lab. The goal was to understand how these drugs might he…

This study tested whether using both an artificial intelligence system (ENDOAID) and a small attachment called Endocuff helps doctors find more polyps during colonoscopy compared to using AI alone. Over 1,700 adults aged 45-85 who needed a colonoscopy took part. The goal was to s…

This study looked at whether a substance called tissue factor (TF) in the blood can help predict how serious colorectal cancer is and if it might come back. Researchers measured TF levels in 26 adults before and after surgery to remove their tumors. The goal was to see if higher …

This study looks at how well the drug T-DXd works compared to usual treatments for people with advanced HER2-positive solid tumors (like lung, colon, and ovarian cancers). Researchers will use data from past clinical trials and real-world patient records to compare survival rates…

This study tested a web-based app called STOMA Care for bladder and colorectal cancer patients who had ostomy surgery and their caregivers. The goal was to see if the app was easy to use and helpful for learning stoma care skills, improving knowledge, and boosting quality of life…

This study looked at 846 people who had a positive stool test for colorectal cancer and needed a follow-up colonoscopy. Researchers wanted to understand how involved patients felt in making decisions about their care and how satisfied they were with the entire screening and treat…

This study explored whether people with intestinal polyps have cancer cells or specific proteins in their blood that could signal early tumor spread. Researchers compared blood samples from 120 patients undergoing colonoscopy—some with polyps, some without. The goal was to find n…

This study involved 132 adults with colorectal cancer who had a standard surgery called low anterior resection with a temporary stoma. The goal was to better understand and define major complications from this surgery, since current reports don't use a single clear safety measure…

This study tested a program to increase colorectal cancer screening and follow-up care in federally qualified health centers, which serve many low-income and uninsured people. The program included training for doctors, reminders for patients and providers, and help navigating car…

This study looked at whether a patient-centered approach called Value-Based Health Care (VBHC) can improve care for people with colorectal cancer. Researchers tracked medical results and patient feedback from 133 participants to see how this approach affects quality of life and t…

This study compared three ways to find precancerous colon polyps during colonoscopy: using an AI system alone, a special cap (Endocuff) alone, or both together. About 481 adults undergoing screening colonoscopy took part. The goal was to see if the combination finds more polyps t…

This study looked at whether different social media messages can motivate people to get screened for colorectal cancer. Over 2,000 adults who identified as White or Black/African American completed a survey after seeing one of five message types. Researchers measured how likely p…

This study looked at 236 adults with breast, pancreatic, or colorectal cancer who sought a second opinion at the University of Colorado. Researchers reviewed medical records to understand why some patients stayed for treatment while others did not. The goal is to learn more about…

This study looked at the best ways to encourage childhood cancer survivors who are at high risk for colorectal cancer to get screened at the recommended age. Researchers tested different methods to see which helped more people complete a colonoscopy or at-home stool test. The goa…

This study looked at whether two simple frailty tests (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients during their treatment to see if those who were frail had more toxicity.…

This study tested whether an educational session at a church could help Spanish-speaking Latinos learn more about colorectal cancer and feel more willing to join cancer clinical trials. Sixty adults attended a session with videos and questionnaires, and 20 also gave one-on-one in…

This study looked at the bacteria in the mouth and gut of 126 people to see if those with serrated polyposis syndrome have a different mix of microbes compared to people with other types of colon polyps or no polyps. Researchers collected saliva and stool samples to analyze the b…

This study examined tumor deposits—small clusters of cancer cells found near the main tumor—in 30 people with colorectal cancer. The goal was to see whether these deposits help predict how long patients live and whether the cancer spreads to other organs. Researchers tracked over…

This study looked at whether adding walnuts to the diet can positively change gut bacteria, reduce inflammation, and improve colon tissue health. Researchers studied 140 adults aged 39-75 who were scheduled for a colonoscopy. Participants ate walnuts daily, and scientists measure…

This study looked at 159 people with advanced colorectal, pancreatic, biliary, or esophageal cancers to see if simple blood tests (tumor markers and liquid biopsies) and patient-reported symptoms could predict whether the cancer would get worse. Researchers compared changes in th…

This study looked at how a digital care planning tool (eHNA) can help personalize care for people with colorectal cancer. Researchers worked with 76 patients and clinicians to understand what works well and what needs improvement. The goal was to identify best practices for using…

This study tested whether an AI computer program could suggest treatments for stomach, colon, and pancreatic cancer that match what experts recommend. Researchers looked at past cases of 30 patients and compared the AI's suggestions to official guidelines and decisions made by a …

This study looked at the gut bacteria of 1,757 people who had colon polyps or colorectal cancer in the past. The goal was to find bacterial markers that could predict who is at high risk for new polyps or cancer. Researchers hope this leads to a simple stool test that could repla…

This study looked at how prostate and colorectal cancer affect the energy-producing parts of cells (mitochondria) and whether a 4-week home exercise program could help. Fifteen men awaiting surgery did either resistance training or high-intensity interval training. Researchers me…

This study looked at whether a special website or two phone calls with a health coach could encourage more people with a personal or family history of certain cancers to get genetic testing. Over 800 adults who already completed a family health survey were randomly assigned to on…

This study looked at whether a care plan led by a geriatrician and a trained nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This study looked at how different diets affect gut bacteria and markers of colon cancer risk in 15 African American adults at higher risk for the disease. Participants ate both a high-fat, animal-based diet and a low-fat, plant-based diet to see which one reduced harmful bacteri…

This study gave educational materials about colorectal cancer and screening to 188 adults aged 45-75 in the Tampa Bay area. Researchers used surveys to measure changes in knowledge and screening intentions over 6 months. The goal was to see if education encourages people to talk …

This study tested a decision aid to help adults aged 76-85 with low health literacy decide about colorectal cancer screening. 60 participants from community health centers used the tool to see if it changed their screening intentions and knowledge. The goal was to improve informe…

This study gathered tissue, blood, and lifestyle information from over 8,000 people scheduled for a colonoscopy. Researchers compared those who had polyps with those who did not, looking for biological, genetic, and lifestyle risk factors. The goal was to better understand what c…

This study looked at whether using a balloon-assisted endoscope (G-Eye) together with artificial intelligence (CAD-Eye) finds more polyps than a standard colonoscopy with AI alone. It included 341 people aged 50-74 who had a positive stool test for colorectal cancer screening. Th…

This study looked at 143 people in China who needed a second surgery after their first rectal cancer operation failed or the cancer came back. The goal was to find out what helps these repeat surgeries succeed in letting patients poop normally again, without a permanent bag. Rese…

This study looked at people with advanced solid tumors (like lung, bladder, or skin cancer) who had been on immunotherapy (PD-1/PD-L1 inhibitors) for one year and whose disease was stable. It randomly assigned them to either stop treatment or continue until their cancer got worse…

This study measured how often colorectal cancer and precancerous polyps occur in endurance athletes aged 35 to 50. Researchers screened 94 male and female runners who had completed long-distance races. The goal was to see if this group has different cancer rates compared to the g…

This study tested a smartphone-based program to help African American men get screened for colorectal cancer. 128 men who were not up-to-date on screening took part. Half received the program with text messages and videos, while the other half got standard educational texts. Rese…

This study tested a program for adults aged 65-90 who had breast, colorectal, or prostate cancer. A community health worker assessed their health and provided coaching to address issues often missed after cancer treatment. The goal was to see if this approach is practical and hel…

This small pilot study tested whether mailing Cologuard or FIT stool tests to adults aged 45-49 helps more people get screened for colorectal cancer. Only 12 people took part, and the goal was to see how many completed screening and how many had abnormal results. The study was no…

This study tested a 12-week web-based diet program with text messaging for 50 colorectal cancer survivors. The goal was to see if the program was easy to use and could help people eat more vegetables, whole grains, and fish while cutting back on red meat and sugary drinks. All pa…

This study analyzed tumor and blood samples from 160 people with esophageal or rectal cancer to find genetic markers that predict how well they respond to chemoradiotherapy given before surgery. The goal was to identify which patients are most likely to benefit from this treatmen…

This study looked at whether a nurse practitioner can safely monitor people with colorectal cancer who are getting intravenous chemotherapy, compared to a doctor. About 207 adults took part. The goal was to see if the number of serious side effects and quality of life were simila…

This study looked at 200 older adults (65+) having planned surgery for colorectal cancer. Researchers used a simple frailty test before surgery to see if it could predict complications like infections or longer hospital stays. The goal is to help doctors better plan care and impr…

This study looked at why some people avoid colorectal cancer screening and whether offering a simple blood test instead of a stool test or colonoscopy could help. Researchers worked with 297 patients from community health centers who had not completed a prior screening order. The…

This study tested a training program for family doctors in Switzerland to help them discuss colorectal cancer screening options (colonoscopy vs. stool test) with patients aged 50-75. The goal was to see if this shared decision-making approach would increase screening rates and be…

This study looked at 598 people who had surgery to remove colorectal cancer. Researchers wanted to learn when and where the cancer might come back after five years. The goal is to help doctors create better follow-up plans to improve survival.

This study looked at 56 people who had surgery for early-stage colon cancer to see if the number and type of immune cells in their tumors could predict whether the cancer would come back. Researchers measured different immune cells in both blood samples and tumor tissue. The goal…

This study looked at whether proteins in the blood can help screen for colorectal cancer. Researchers tested blood samples from 350 people who were already scheduled for a colonoscopy. The goal was to see if certain protein markers could reliably spot advanced growths, and to fin…

This study tested a digital tool (a chatbot) to help cancer survivors learn about genetic testing for hereditary cancer risk. 50 adults who had certain cancers (like breast, ovarian, or prostate) took part. The goal was to see if the chatbot was easy to use and if it helped more …

This study tested a program that uses computer algorithms and patient navigators to help people in low-income areas complete their colorectal cancer screening. 385 adults from specific Philadelphia zip codes who had not finished a colonoscopy or stool test were included. The goal…

This study looked at whether sending text message reminders could boost the number of people who complete colorectal and breast cancer screening. Over 44,000 eligible adults participated. The goal was to see if simple SMS reminders are more effective than standard letters alone, …

This study examined how the COVID-19 pandemic affected colorectal cancer diagnosis and treatment in 198 patients in Hungary. Researchers compared cancer stages and diagnostic delays across different pandemic waves. The goal was to understand the impact of healthcare disruptions o…

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study looked at 698 people with advanced colorectal cancer to see if inflammation in the body changes how well a targeted therapy (bevacizumab) combined with chemotherapy works. Researchers measured inflammation markers in the blood and tracked survival and tumor response. T…

This study looked at whether certain genetic changes in colon cancer tumors can help predict if the cancer will return after surgery. Researchers tested tumor tissue from 401 people with stage II or III colon cancer using a special method called QMPSF. The goal was to see if thes…

This study tested whether wearable wristbands that track heart rate, sleep, and steps can help patients recover faster after colorectal cancer surgery. 192 patients wore the device for about a week after surgery and filled out daily forms. The goal was to see if early walking red…