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Simple gel may shield cancer patients from debilitating Hand-Foot rash

NCT ID NCT07177560

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 32 times

Summary

This study looked at whether applying a diclofenac gel to the hands and feet can prevent or delay hand-foot syndrome—a painful skin reaction—in people with colorectal or stomach cancer taking the chemotherapy drug capecitabine. About 150 patients were observed, with some using the gel and others just monitored. The goal was to see if the gel reduces severe skin problems and helps patients stay on their cancer treatment.

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Contacts and locations

Locations

  • Ankara Etlik City Hospital

    Ankara, Turkey (Türkiye)

  • Gazi University

    Ankara, Turkey (Türkiye)

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm gastric cancer gastric neoplasm hand-foot syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.