GASTRIC CANCER (GC)

This study is testing whether adding two new immunotherapy drugs to standard chemotherapy works better for people with advanced stomach cancer that hasn't been treated before. About 32 participants will receive the drug combination by IV and pills, continuing on a maintenance the…

This study is looking at whether washing the abdomen with heated chemotherapy during stomach cancer surgery helps prevent the cancer from coming back in that area. It will involve 200 people with advanced stomach cancer that has a high risk of spreading inside the abdomen. Resear…

This study is testing two different drug combinations for people with advanced stomach or gastroesophageal junction cancer whose disease has continued to grow despite receiving first-line immunotherapy. Researchers want to see if adding a third drug to a two-drug combination is m…

This study is testing a combination of radiation, chemotherapy, and two immunotherapy drugs given before surgery for stomach cancer. The goal is to see if this approach can shrink or eliminate the tumor to make surgery more successful. Researchers will compare two different order…

This study is comparing two different chemotherapy combinations given after surgery for stage III stomach cancer. It aims to see if one treatment is as good as or better than the other at keeping the cancer from coming back. About 387 patients who have had their tumor surgically …

This study aims to find the best way to reconnect the digestive system after surgery to remove the upper part of the stomach for cancer. Researchers will compare several different surgical reconnection techniques in 300 patients to see which one leads to fewer complications, less…

This is an early safety study testing an experimental drug called SH009 injection in adults with advanced solid tumors who have run out of standard treatment options. The study aims to find a safe dose, see how the body processes the drug, and check for early signs that it might …

This study is testing a new camera-based imaging method against the current standard to see which is better at checking blood flow in tissue during surgery for stomach or colorectal cancer. The goal is to help surgeons make better decisions during the operation to prevent serious…

This study aims to develop a simple blood test to detect six different gastrointestinal cancers earlier than current methods. Researchers will analyze blood samples from 1,000 people, including those with cancer and healthy controls, to find tiny genetic signals that indicate can…

This study is testing a new type of PET/CT scan called [¹⁸F]FAPI-74 to see if it can better detect when stomach or esophageal cancer has spread to other parts of the body. The trial will involve 200 adults with these cancers who are being evaluated for treatment. Researchers will…

This study aims to better understand how stomach cancer spreads to nearby lymph nodes. Researchers will observe 400 patients undergoing surgery for advanced lower stomach cancer to see which specific lymph node areas are most often affected. The goal is to gather information that…