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New blood test could spot six gut cancers before symptoms start

NCT ID NCT07224750

First seen Nov 05, 2025 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study is developing a blood test that looks for tiny genetic molecules called miRNAs, which can signal the presence of several gastrointestinal cancers like liver, pancreatic, and colorectal cancer. Researchers will analyze blood samples from 1,000 adults—half with cancer and half without—to see how accurately the test can distinguish between them. The goal is to create a noninvasive, affordable screening tool that could catch these cancers earlier, when they are easier to treat.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Nat Medical Ctr

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

miRNA blood test

What this could lead to

If successful, this could lead to a simple, noninvasive blood test for early detection of several gastrointestinal cancers, improving survival rates.

What could go wrong

This is an early-stage study focused on diagnostic accuracy, not treatment. The test may not be sensitive or specific enough for widespread use, and further validation is needed.

Conditions

The condition(s) this trial relates to.

cholangiocarcinoma colorectal cancer digestive system neoplasm esophageal squamous cell carcinoma gastric cancer gastric neoplasm hepatocellular carcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.