GASTRIC CANCER (GC)

This study compares two types of minimally invasive surgery for stomach cancer that has spread to the outer stomach wall (cT4a). About 335 adults aged 18-80 will be randomly assigned to have their tumor removed with either robot-assisted or laparoscopy-assisted surgery. The main …

This study tests a combination of three drugs (sintilimab, bevacizumab, and chemotherapy) in people with a rare and aggressive type of stomach cancer that produces high levels of a protein called AFP. The goal is to shrink the tumor enough so it can be removed by surgery. About 4…

This study tests a new treatment for people with advanced stomach cancer that has not spread to other parts of the body or has spread a little. The treatment combines two immunotherapy drugs, chemotherapy, and targeted radiation. The goal is to see if this combination can shrink …

This early-phase study tests a new cell therapy called NK510 in 15 people with advanced stomach or colorectal cancer that has not responded to or returned after at least two prior treatments. The therapy is given through an IV or directly into the abdomen. The main goals are to c…

This study tests a new drug called QLS5132 given with other cancer treatments for people with advanced solid tumors, including stomach, lung, endometrial, and ovarian cancers. The goal is to find safe doses and see if the combination can shrink tumors. About 626 participants will…

This study tests a new drug, JPI-547, combined with the chemotherapy irinotecan for people with advanced stomach cancer that has come back or spread. It is for patients who have already tried at least two other treatments. The goal is to see if the combination is safe and can shr…

This study aims to see if a new sensor can find tiny particles called extracellular vesicles in stomach fluid to help diagnose gastric cancer. Researchers will collect stomach fluid from 100 people during an endoscopy and test it with a special light-based sensor. The goal is to …

This study tests a new type of PET scan that uses a special probe to find cancers that have a protein called GPA33. The study will include 56 people with suspected or confirmed colorectal, stomach, or pancreatic cancer, as well as healthy volunteers. The goal is to see if this im…

This study tests a new ultrasound technique to see if it can predict whether chemotherapy is working for stomach cancer that has spread to the liver. Currently, doctors wait about 2 months for CT or MRI scans to show tumor changes. This ultrasound looks at blood flow inside the t…

This study looks at whether tumor DNA found in blood or belly fluid can predict if stomach, colon, or pancreatic cancer will spread to the lining of the abdomen (peritoneum). Researchers will follow 300 patients with early-stage cancers to see if those with positive tumor DNA hav…