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New study compares promising drug to standard care for multiple HER2-Positive cancers

NCT ID NCT06973161

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 36 times

Summary

This study looked at how well the drug T-DXd works compared to standard treatments for people with several types of HER2-positive cancers that have spread. Researchers used data from past trials and real-world patient records to compare survival. The goal was to see if T-DXd offers a better chance of living longer for these patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Spartanburg, South Carolina, 29303, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Vienna, Austria

  • Research Site

    Liège, Belgium

  • Research Site

    London, Ontario, N6A 5A5, Canada

  • Research Site

    Olomouc, Czechia

  • Research Site

    Copenhagen, Denmark

  • Research Site

    Caen, France

  • Research Site

    Lille, France

  • Research Site

    Marseille, France

  • Research Site

    Nice, France

  • Research Site

    Paris, France

  • Research Site

    Saint-Herblain, France

  • Research Site

    Berlin, Germany

  • Research Site

    Essen, Germany

  • Research Site

    Frankfurt, Germany

  • Research Site

    Heidelberg, Germany

  • Research Site

    Würzburg, Germany

  • Research Site

    Meldola, Italy

  • Research Site

    Rome, Italy

  • Research Site

    Porto, Portugal

  • Research Site

    Barcelona, Spain

  • Research Site

    Madrid, Spain

  • Research Site

    Pamplona, Spain

  • Research Site

    Valencia, Spain

  • Research Site

    Leeds, United Kingdom

  • Research Site

    London, United Kingdom

Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms cervical cancer colorectal adenocarcinoma colorectal cancer colorectal neoplasm endometrial cancer endometrium neoplasm lung cancer lung neoplasm malignant pancreatic neoplasm non-small cell lung carcinoma ovarian cancer ovarian carcinoma pancreatic neoplasm urinary bladder carcinoma Urinary Bladder Neoplasms Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.