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8,000 volunteers help uncover colon polyp risks

NCT ID NCT00625066

Knowledge-focused Sponsor: Vanderbilt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and health to find possible risk factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

8,108 people

The number who actually took part.

Started

Jan 2003

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

participants who are planning to undergo colonoscopy

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

DISEASE CHARACTERISTICS: * Scheduled to undergo colonoscopy at the Vanderbilt University Medical Center or the Tennessee Valley Veterans Administration Medical Center * No prior genetic colorectal cancer syndromes or colorectal adenoma PATIENT CHARACTERISTICS: * Must have a permanent residence and a telephone number * Able to speak and understand English * No prior inflammatory bowel disease * No prior cancer other than nonmelanoma skin cancer * Not a current resident in a correctional facility * No other rare exclusion that would prevent the collection of study data (e.g., extensive memory loss for past exposures), impair ability to provide informed consent, or make the participant an atypical colonoscopy patient (e.g., colonoscopy for organ transplant evaluation) * No prior extensive knowledge or contact with the investigation/protocol/hypotheses (the study collaborator or reviewer) PRIOR CONCURRENT THERAPY: * No prior partial or complete colon resection * No concurrent participation in a clinical trial involving the prevention of colon polyps

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal adenoma colorectal cancer colorectal neoplasm polyp of large intestine precancerous condition rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer Precancerous condition

Contacts and locations

Locations

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, 37232-6838, United States

  • Vanderbilt-Ingram Cancer Center - Cool Springs

    Nashville, Tennessee, 37064, United States

  • Vanderbilt-Ingram Cancer Center at Franklin

    Nashville, Tennessee, 37064, United States

  • Veterans Affairs Medical Center - Nashville

    Nashville, Tennessee, 37212, United States

More trials for these conditions

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