COLORECTAL CANCER

This study tests a two-drug combination (cabozantinib and nivolumab) in people with advanced colorectal cancer that is microsatellite stable (MSS) and has stopped responding to standard treatments. The goal is to see if the combination can control the cancer for at least 16 weeks…

This study tests a different way of taking the chemotherapy drug capecitabine for colorectal cancer. Instead of the standard daily dosing, patients take the drug for 7 days, then take a 7-day break. The goal is to see if this schedule improves quality of life while still controll…

This early-stage study tests a new drug called TORL-3-600 in 70 adults with advanced solid tumors or colorectal cancer that has not responded to other treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. Participants must have…

This early-phase study tests whether giving healthy donor natural killer (NK) cells along with two drugs (vactosertib and IL-2) is safe and helps the cells stay active in people with advanced colorectal, stomach/esophageal, or blood cancers. The NK cells are meant to attack cance…

This study is for people with advanced solid tumors (like lung, bladder, or skin cancer) that have stopped responding to standard immunotherapy drugs called PD-1/PD-L1 inhibitors. Researchers are testing a new combination of immune-boosting drugs to see if they can shrink tumors …

This study tests if a special 'figure-of-X' stitching method can lower the risk of the belly wound bursting open after colorectal cancer surgery, compared to the usual continuous stitch. About 40 adults having open surgery will take part. The goal is to see which method leads to …

This study looks at how long doctors should wait after chemoradiation before performing surgery on patients with stage II or III rectal cancer. About 248 people will receive radiation plus chemotherapy (with or without extra drugs) before surgery. The goal is to find the best tim…

This study aimed to see if immune checkpoint drugs (nivolumab with or without ipilimumab) could help people with colorectal or gastroesophageal cancer delay or avoid major surgery. It planned to enroll adults with early-stage cancers. However, the study was withdrawn before any p…

This early-stage study tests a new drug called ELVN-002 combined with trastuzumab (and sometimes chemotherapy) in people with advanced HER2-positive cancers, including breast, colorectal, and gastric cancers. The main goal is to find a safe dose and check for side effects. About …

This early-phase study tests a new drug called AI-061, which combines two immunotherapy agents (anti-PD-1 and anti-CTLA-4) into one treatment. The goal is to find the safest dose and see if it can shrink tumors in people with advanced cancers like melanoma, lung, and ovarian canc…

This early-stage trial tests a new treatment for people with advanced solid tumors (like head and neck, melanoma, or lung cancer) that haven't responded to standard therapies. Doctors take a patient's own immune cells from the tumor, pick out the ones best at fighting cancer, gro…

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard stereotactic radiation can better control brain metastases that are at high risk of coming back after radiation alone. About 134 adults with brain tumors from cancers like melanoma, lung, breast, or …

This study is for people with advanced colorectal cancer that has a specific genetic change called a KRAS mutation and has stopped responding to standard treatments. Researchers are testing the safety and effectiveness of combining two drugs, AVUTOMETINIB and cetuximab. The goal …

This early-stage study tests a new drug called M9140 in 12 Chinese adults with advanced colorectal cancer that has not responded to standard treatments. The drug is designed to target and kill cancer cells while limiting harm to healthy cells. The main goals are to check safety a…

This study tests a combination of team-based clinic changes and a patient app to help more people complete a colonoscopy after an abnormal stool-based cancer screening. About 2,000 adults who speak English, Spanish, or Cantonese and had an abnormal FIT result will take part. The …

This study tests a temporary device called Colovac that is placed inside the bowel after colorectal cancer surgery to protect the surgical connection. The goal is to see if it can help patients avoid a temporary ileostomy (a stoma bag) and reduce serious complications. About 108 …

This study tests whether a special low-calorie diet, called a fasting-mimicking diet, given before and after surgery can help colorectal cancer patients recover faster and reduce the chance of cancer coming back. About 600 patients undergoing their first colorectal cancer surgery…

This study compares two ways to give chemotherapy directly into the abdomen after surgery to remove visible cancer in people with appendix or colorectal cancer that has spread to the lining of the belly. One method gives chemotherapy right after surgery through a tube, and the ot…

This study tests a combination of three drugs (fruquintinib, an immunotherapy, and an oral chemo) in people with advanced colorectal cancer that has not responded to standard second-line therapy. About 106 participants will receive the combo to see if it can shrink tumors and ext…

This study tests a new drug called LY4066434 in people with advanced solid tumors that have certain KRAS mutations. The main goal is to see if the drug is safe and tolerable when given alone or with other treatments. About 750 participants with cancers like pancreatic, lung, or c…

This phase 2 study tests a combination of three drugs (Tislelizumab, Fruquintinib, and Metronidazole) in 33 adults with advanced colorectal cancer that has not responded to prior treatments. The study focuses on patients with high levels of Fusobacterium nucleatum in their stool.…

This study tests whether adding extra stitches around the surgical connection after removing low rectal cancer can lower the risk of leaks, a serious complication. About 300 adults with low rectal cancer will be randomly assigned to get either standard surgery or surgery with rei…

This study tests an experimental drug called MCLA-129 in people with advanced non-small cell lung cancer and other solid tumors that have stopped responding to standard treatments. The drug is a bispecific antibody designed to block two cancer-related proteins (EGFR and c-MET) at…

This study tests whether giving chemotherapy before and after surgery (plus heated chemotherapy during surgery) helps people with colorectal cancer that has spread to the abdomen lining live longer compared to surgery alone. About 358 adults with resectable cancer will be randoml…

This early-stage study tests an experimental drug called telisotuzumab adizutecan in about 30 Chinese adults with advanced colorectal cancer that cannot be removed by surgery. The main goals are to check safety and how the drug moves through the body. Participants receive differe…

This study tests an experimental drug called entrectinib in people with advanced solid tumors that have certain gene changes (NTRK, ROS1, or ALK). The drug aims to shrink or control the cancer by blocking signals that help it grow. About 534 adults with various cancers, including…

This study tests whether a nurse-led program can help women aged 45-64 in Hong Kong better manage their health and use medical resources wisely. Over 1,700 participants will either receive personalized nurse guidance or general health advice. The goal is to improve health confide…

This study tests whether a new drug combination (XL092 plus atezolizumab) works better than the current standard drug regorafenib for people with advanced colorectal cancer that has spread. About 900 adults whose cancer did not respond to or stopped responding to standard treatme…

This study tests two drugs, regorafenib and lorigerlimab, in people with high-risk colorectal cancer who have tiny traces of cancer DNA in their blood after finishing standard treatments. The goal is to see if the combination can clear these hidden cancer cells and improve outcom…

This study tests whether adding a targeted treatment (local ablative therapy) to standard chemotherapy can help people with colorectal cancer that has spread to a few spots live longer without the cancer growing. About 6 participants whose cancer responded to initial chemotherapy…

This study tests whether taking low-dose aspirin daily can improve survival in people with colorectal cancer that has specific genetic changes (PI3K pathway mutations). About 626 patients who had surgery for stage II or III colon or rectal cancer are taking either aspirin or a pl…

This study tests a personalized approach for colorectal cancer patients who have a high chance of the cancer returning after surgery. Researchers create a custom immune treatment based on the patient's own tumor and combine it with standard chemotherapy. The goal is to see if thi…

This program offers an unapproved drug, fruquintinib, to adults with metastatic colorectal cancer that has worsened after all standard treatments. It is for people who cannot join a clinical trial and have no other options. The goal is to provide access until the drug becomes com…

This study tests a low dose of the immunotherapy drug nivolumab, alone or with chemotherapy, in people with advanced colorectal or stomach cancers that have a specific genetic feature (MSI/dMMR). The goal is to see if this approach can shrink tumors before surgery or control the …

This early-stage study tests an investigational drug called ABBV-400, alone or with another drug (bevacizumab), in about 520 adults with advanced solid tumors including lung, stomach, and colorectal cancers. The goal is to find the safest and most effective dose and see if it can…

This early-phase study tests a new drug, GDC-6036, in people with advanced cancers (like lung or colorectal) that have a specific KRAS G12C mutation. The main goals are to check safety and find the right dose, either alone or with other cancer treatments. About 500 participants w…

This study aimed to test two immunotherapy drugs (tiragolumab and atezolizumab) plus targeted radiation in people with a type of metastatic colorectal cancer that doesn't respond to standard immunotherapy. The trial was withdrawn before any participants enrolled, so no results ar…

This study tests whether adding an experimental drug (HR070803) to standard chemotherapy and targeted therapy can help people with advanced colorectal cancer live longer without their cancer growing. About 669 adults with stage IV colorectal cancer that cannot be removed by surge…

This study looks at whether aerobic exercise can lower ctDNA levels in the blood, which may help prevent cancer from returning. About 33 people who have been treated for high-risk breast, prostate, or colorectal cancer will try different amounts of weekly exercise to find the saf…

This study looks at 60 adults with left-sided colorectal cancer who are having surgery to remove the tumor. It compares two methods of bowel preparation: mechanical cleaning alone versus mechanical cleaning plus oral antibiotics. The goal is to see which approach reduces surgical…

This study tests a new drug called XS-03 combined with standard chemotherapy and bevacizumab in people with metastatic colorectal cancer that has a RAS mutation. The goal is to see if the combination is safe and helps shrink tumors. About 102 adults aged 18 to 70 are being enroll…

This early-stage study tests an experimental pill called HBI-2376 in people with advanced solid tumors (like lung, colon, or pancreatic cancer) that have specific gene changes (KRAS or EGFR mutations). The main goals are to find the safest dose and understand how the drug moves t…

This early-stage study tests a new drug, HBI-2438, in people with advanced cancers (like lung, colon, or pancreatic) that have a specific genetic mutation called KRAS G12C. The main goals are to find a safe dose and understand how the drug moves through the body. About 44 adults …

This study tests a new targeted drug (JAB-21822) combined with standard chemotherapy and bevacizumab in 30 Chinese adults with advanced colorectal cancer that has a specific KRAS G12C mutation and has stopped responding to first-line treatment. The goal is to see if the combinati…

This early-phase study tests an experimental cell therapy called P-MUC1C-ALLO1 in 180 adults with advanced solid tumors (e.g., breast, ovarian, lung, pancreatic cancers) that have not responded to standard treatments. The therapy uses donor immune cells engineered to target a pro…

This early-phase study tests a vaccine targeting mutant KRAS proteins, combined with two immunotherapy drugs (nivolumab and ipilimumab), in patients with colorectal or pancreatic cancer that has been surgically removed. The goal is to see if the combination is safe and boosts the…

This study is for adults with colorectal cancer that has spread to the liver and who are scheduled for surgery to remove the liver tumors. The goal is to see if taking a study drug called QBECO (self-injected at home) before and after surgery can lower the chance of the cancer co…

This study tests whether retreating with a combination of two targeted drugs (encorafenib and cetuximab) can shrink tumors in people with a specific type of advanced colorectal cancer (BRAF V600E mutation). Participants must have previously benefited from the same drugs and still…

This study tests a new immunotherapy called ELI-002 7P for people with pancreatic or other solid tumors that have certain gene mutations (KRAS/NRAS). The treatment aims to help the immune system fight cancer cells after standard treatments like surgery and chemotherapy. About 158…

This study compares two sequences of drugs (panitumumab followed by regorafenib versus the reverse order) in 214 patients with advanced colorectal cancer that no longer responds to standard treatments. Participants must have previously benefited from an anti-EGFR therapy and have…

This early-phase trial tests a treatment for adults with metastatic solid tumors (like colorectal, lung, or breast cancer) that have a specific genetic change called KRAS. Doctors take a person's own white blood cells, modify them in a lab to better recognize and attack cancer ce…

This study was designed to test a combination of two drugs (regorafenib and lorigerlimab) given before surgery to people with a certain type of colorectal cancer that had spread only to the lungs. The goal was to see if the treatment was safe and could shrink tumors enough to imp…

This study is testing an experimental drug called AZD5305, a PARP inhibitor, in people with advanced solid tumors like ovarian, breast, pancreatic, and prostate cancer. The goal is to see if the drug is safe and tolerable when given alone or with other cancer treatments. About 70…

This study is for people with advanced solid tumors (like lung or colorectal cancer) that have a specific genetic change called KRAS G12C. It tests a new drug, JDQ443, combined with other treatments to see if they are safe and can shrink tumors. About 74 adults will take part. Th…

This study tests two immunotherapy drugs, botensilimab and balstilimab, in 16 people with advanced colorectal cancer that has spread. The goal is to see if the combination can shrink or stabilize tumors. If the cancer progresses, standard chemotherapy is added. Participants are f…

This study tests a new experimental drug, HFB200603, either alone or combined with another cancer drug (tislelizumab), in adults with advanced solid tumors like kidney, lung, skin, stomach, or colorectal cancer. The goal is to find safe doses and understand side effects. About 83…

This early-stage study tests a new drug called IMT-009 in people with advanced solid tumors or lymphomas that have not responded to standard treatments. The main goals are to find a safe dose and learn about side effects. About 67 participants will receive the drug intravenously,…

This study was planned to test two drugs, Ezabenlimab and BI 907828, in people with advanced solid tumors like sarcoma, lung, breast, colorectal, or bile duct cancer. The goal was to see if the combination could control tumor growth for at least 24 weeks. However, the study was w…

This study was designed for people with a certain genetic form of advanced colorectal cancer that had spread. It aimed to test whether adding the drug inavolisib to standard chemotherapy and another targeted drug could shrink tumors or slow the disease. However, the study was wit…

This study looks at whether following a healthy diet can improve long-term survival and reduce the chance of cancer returning in people who have had colorectal cancer. About 500 participants with stage I to III colorectal cancer are taking part. Researchers are focusing on a diet…

This study tests two experimental drugs, AK119 and AK112, alone or with chemotherapy, in 170 adults with a specific type of colorectal cancer (pMMR/MSS) that often doesn't respond well to standard treatments. The goal is to see if these combinations can shrink tumors or slow the …

This early-phase study tests the safety of a drug called tucatinib in about 25 Chinese patients with advanced HER2+ breast, stomach, or colorectal cancers that have stopped responding to standard treatments. The main goal is to see what side effects occur and how the drug moves t…

This study tests the drug pembrolizumab in 25 adults with a specific type of advanced colorectal cancer (dMMR) that cannot be surgically removed. The goal is to see if the drug can shrink tumors enough to allow surgery or avoid it altogether. Participants receive pembrolizumab an…

This early-phase trial tests a new drug called adagrasib (MRTX849) combined with two other drugs (cetuximab and irinotecan) in people with colorectal cancer that has a specific genetic change (KRAS G12C). The main goal is to find a safe dose and check for side effects. About 24 a…

This study tests a new combination of two immunotherapy drugs (MK-1308A) against other treatments for people with a specific type of advanced colorectal cancer (MSI-H/dMMR). The goal is to see if the new combo can shrink tumors or slow the disease. About 302 adults with stage IV …

This study aimed to see if a person's own immune cells, modified in a lab to target specific cancer gene mutations, could prevent gastrointestinal cancers from coming back after standard treatment. It was designed for people with certain gene changes and blood markers suggesting …

This study checks how well a new stool test called LifeKit® finds colorectal cancer and precancerous polyps. About 12,000 adults aged 40 and older who are already scheduled for a screening colonoscopy will provide a stool sample. The goal is to see if the test is accurate enough …

This study compares two non-invasive stool tests (DNA and FIT) to standard colonoscopy for detecting colorectal cancer and precancerous growths in 350 adults with cystic fibrosis. The goal is to see if these simpler tests can accurately identify cancer or polyps, potentially redu…

This study looks at whether a simple blood test that checks for circulating tumor DNA can help decide who really needs a colonoscopy after a diverticulitis attack. About 220 participants will give a blood sample and then have a colonoscopy as usual. Researchers will compare the b…

This study tests whether sending a colorectal cancer screening test directly to people's homes (without needing to order it) increases the number of people who get screened. About 64,000 adults aged 50-74 in central France will be randomly assigned to receive the test by mail or …

This study tests whether a digital program (mPATH-Cloud) helps more people complete colorectal cancer screening compared to usual care. About 1,000 adults aged 45-73 who are overdue for screening take part. The program sends a text or letter inviting them to a website where they …

This study compares two colorectal cancer screening methods—a stool test and a scope exam—in 140,000 adults aged 50-74 in Norway. The goal is to see which approach works best to catch cancer early and reduce deaths. Participants are average-risk men and women living in specific a…

This large study compares two common colorectal cancer screening methods: colonoscopy and an annual at-home stool test (FIT). About 50,000 veterans aged 50-75 will be randomly assigned to one of the two screenings and followed for 10 years. The goal is to see which approach bette…

This study compares time-restricted eating (eating only during a set daily window) to traditional calorie counting for weight loss and reducing colorectal cancer risk. About 193 adults with obesity, aged 45-70, will follow one of the two diets for a period. The goal is to see if …

This study looks at whether taking a daily aspirin can reduce the risk of colorectal cancer in people who have already had a precancerous polyp (adenoma) removed. Researchers will measure certain chemicals in the body that are linked to inflammation and cancer risk. The goal is t…

This study tests whether sending reminders and using doctor alerts can help more people get screened for colorectal cancer. About 20,000 patients aged 50-72 who are overdue for screening will take part. The goal is to see if these gentle pushes increase the number of people who c…

This large study is testing whether screening with a flexible tube (sigmoidoscopy) can lower the number of colorectal cancer cases and deaths. About 100,000 men and women aged 50-64 in Norway are taking part. The researchers also want to see if adding a stool blood test helps, an…

This study looks at whether taking low-dose aspirin can lower the risk of colorectal cancer in people who have already had precancerous polyps removed. Researchers will measure changes in certain stem cell markers in the colon and other substances in the blood and urine. The goal…

This study tests whether mailing at-home stool tests (FIT) to people who are due for colorectal cancer screening can increase screening rates in underserved Brooklyn communities. About 3,000 adults aged 45-75 who get care at certain health centers will take part. The goal is to c…

This study tests whether personalized screening—using stool tests, blood tests, and risk scores—can better prevent stomach and colon cancer in adults aged 50-75. Researchers will enroll 40,000 healthy participants and track them over time. The goal is to find the most effective w…

This study looks at whether a 16-week home exercise program can help Black and Hispanic patients with breast, colorectal, or prostate cancer become more active while on chemotherapy. Participants are split into three groups: supervised exercise via Zoom, unsupervised exercise, or…

This study tests whether talking to an exercise specialist over the phone can help breast and colorectal cancer survivors become more physically active after finishing chemotherapy. About 120 adults who completed treatment for early-stage cancer will be randomly assigned to recei…

This study tests whether a therapist-guided online program (TG-iConquerFear) can help colorectal cancer survivors who have finished treatment reduce their fear of cancer coming back. About 200 participants will be randomly assigned to either the online therapy or standard care. T…

This study tests whether live exercise coaching plus a personalized digital app can improve quality of life for cancer survivors. About 146 adults with breast, lung, prostate, colorectal, or other cancers who had treatment in the last year will use the program for 18 months. Rese…

This study looks at a program called CARES-REACH designed to increase colorectal cancer screening rates in rural clinics. Researchers will track how many people complete a simple stool test (FIT) and see if factors like income, language, or insurance affect screening. The goal is…

This study looks at how Western habits—like drinking alcohol and eating late—might increase the risk of colorectal cancer. Twelve adults who have had colon polyps in the past will try four different weekly routines, including eating at normal times or late, with or without alcoho…

This study collects fresh tumor samples from 416 adults with various cancers (bladder, kidney, colorectal, head and neck, liver, lung, skin, endometrial) to develop and train a live tumor diagnostic platform. The goal is to see how accurately the platform can predict whether a pa…

This study looks at ways to help people who have inherited gene changes that raise cancer risk. The goal is to see if certain tools can help them follow recommended cancer screening and prevention steps, and also share their genetic test results with family members. About 720 adu…

This study looked at whether certain genes that make people more prone to bleeding can cause a stool test for colon cancer to show a false-positive result. Researchers planned to collect saliva samples from people who had a raised stool blood test but a normal colonoscopy, and co…

This study follows 637 people with a specific type of colorectal cancer called MSI. Researchers want to find biological markers that can predict how the cancer will behave and whether chemotherapy will help. The goal is to better understand this cancer type and guide treatment de…

This study looks at whether a simple blood test can find tiny bits of cancer DNA left in the body after colorectal cancer surgery. The goal is to identify patients at high risk of the cancer coming back, so doctors can adjust treatment early. Over 3,000 participants are being fol…

This study aims to increase colorectal cancer screening among African Americans aged 45-72 who get care at community health centers in Michigan. Participants will learn about screening options (colonoscopy, stool tests) and choose one. Then they are randomly assigned to receive u…

This study looks at gene changes in tumor samples from 787 people with advanced or recurrent colorectal cancer who took part in an earlier trial. Researchers want to see if certain gene patterns are linked to how long patients lived or how long their cancer stayed under control. …

This study follows over 64,000 adults who grew up on farms to see if early-life exposures to pesticides and other agricultural factors are linked to cancer. Participants fill out an online questionnaire and may provide biological samples. Researchers will track cancer and other d…

This study tests a special camera that measures oxygen levels in the bowel during surgery to help doctors see if the blood supply is good. It involves 52 adults having laparoscopic colorectal surgery for cancer or diverticulitis. The goal is to see if this imaging can predict and…

This study looks at 67 people in Denmark who had early-stage colorectal cancer removed during a colonoscopy or minor surgery. Doctors often recommend more surgery because of certain risk factors, but only about 15% actually have leftover cancer. The researchers are testing a bloo…

This study looks at whether providing easy-to-understand information can help relatives of people with Lynch syndrome decide whether to get genetic counseling or testing. About 185 adult family members will be randomly given either a standard letter or a letter plus a booklet. Re…

This study uses artificial intelligence to find people aged 45-49 who are at higher risk for colorectal cancer and then helps them get screened. About 7,120 participants will either receive extra support to complete a stool test or colonoscopy, or get the usual care. The goal is …

This study tests a dye mixture (ICG and hyaluronic acid) that doctors inject into the colon wall near a tumor during a colonoscopy. The dye glows under a special camera during surgery, helping surgeons see exactly where the tumor is. The goal is to make colon cancer surgery more …

This study is looking back at medical records of 700 adults with colorectal cancer that has spread to the brain. Researchers want to see how different local treatments (like surgery or radiation) affect how long patients live and how long it takes for the cancer to grow again in …

This study is testing a blood test that looks for tiny bits of tumor DNA (ctDNA) to see if it can predict when colorectal cancer might return after surgery. About 1,000 people with stage II or III colorectal cancer who had their tumor completely removed will be followed for up to…

This study compares two types of emergency colon surgery: keyhole (laparoscopic) and traditional open surgery. Researchers want to see which approach leads to fewer complications and better long-term survival. About 192 adults needing urgent colon removal are taking part.

This study is a national registry in Italy that collects health information from 1,500 people with familial adenomatous polyposis (FAP) and related conditions. The goal is to better understand how these diseases progress, how they are currently managed, and how to improve care. N…

This study compares two ways of monitoring colorectal cancer patients after surgery: standard CT scans versus a new approach that also uses a blood test (ctDNA) to find cancer DNA. The goal is to see if the blood test helps detect cancer recurrence earlier and allows more patient…

This study aimed to test three advanced imaging techniques to help surgeons see colorectal tumors more clearly during operations. The goal was to improve how completely tumors are removed. However, the study was withdrawn before enrolling any participants, so no results are avail…

This study collects blood samples from 102 people with non-small cell lung cancer, colorectal cancer, or pancreatic cancer to track genetic changes in tumor DNA over time. Participants continue their standard treatments while researchers measure how cancer DNA levels in the blood…

This study looks at tissue samples from 582 people with colon cancer, colon polyps, or healthy colons to compare cancer-related markers and gut bacteria. The goal is to better understand how colon cancer develops, not to test a new treatment. Results may help future detection or …

This study looks at whether special blood tests can help doctors know if treatment is working and if cancer will come back in people with colorectal cancer that has spread to up to 5 spots in the liver or lungs. About 120 patients will give blood samples before, during, and after…

This study looks at tumor samples from over 3,000 people with advanced cancers to find specific genetic markers (biomarkers). The goal is to help doctors choose which targeted therapy clinical trials might work best for each patient. It does not test a new treatment itself, but a…

This study tests whether giving doctors real-time feedback during colonoscopy helps them find more polyps, which can prevent colorectal cancer. Over 4,000 doctors will participate, and the main goal is to see if the feedback improves the rate of polyp detection. The study is curr…

This study looks at how well a stoma works and how it affects quality of life in people with colorectal cancer. It compares those who had emergency stoma surgery with those who had planned surgery. About 700 participants will fill out a questionnaire about their stoma function an…

This study looks at two new models of care for people who have finished treatment for early-stage breast or colorectal cancer. The goal is to see if these models help survivors get the recommended follow-up tests and preventive care they need. About 2,450 adults from Kaiser Perma…

This study aims to help rural clinics in Indiana get more people screened for colorectal cancer. Researchers will use methods like mailing test kits, sending text reminders, and assigning patient navigators to guide people through the process. The study involves clinic staff and …

This study looks at genetic markers in tumor tissue to see if they can predict how well two different chemotherapy combinations work for people with advanced colorectal cancer. About 757 patients who have not had chemotherapy before will be randomly assigned to one of two treatme…