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Nanoparticles may help radiation zap stubborn brain tumors

NCT ID NCT04899908

First seen Apr 30, 2026 · Last updated May 22, 2026 · Updated 7 times

Summary

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard stereotactic radiation can better control brain metastases that are at high risk of coming back after radiation alone. About 134 adults with brain tumors from cancers like melanoma, lung, breast, or colorectal cancer will be randomly assigned to receive radiation with or without the nanoparticles. The main goal is to see if the combination delays tumor regrowth in the brain.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.