Nanoparticles boost radiation for brain tumors in new trial

NCT ID NCT04899908

First seen Apr 30, 2026 · Last updated May 08, 2026 · Updated 3 times

Summary

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard stereotactic radiation can better control brain metastases that are at higher risk of coming back after radiation alone. About 134 adults with cancers like melanoma, lung, breast, or colorectal cancer that have spread to the brain are participating. The nanoparticles are designed to make radiation more effective at killing tumor cells while sparing healthy tissue.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.