Scientists hunt for clues in colon cancer and polyp tissues
NCT ID NCT05638542
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at genetic and molecular markers in tissue and stool samples from people with colon cancer, colon polyps, and healthy controls. Researchers aim to understand how these markers differ and how they relate to cancer development. The study involves 582 participants and uses advanced techniques to analyze DNA, proteins, and gut bacteria.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify which markers signal early cancer risk, potentially improving screening or prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to direct patient benefits, and findings may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
582 people
The number who actually took part.
- Started
-
Mar 2015
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who visited Seoul National University Bundang Hospital for gastrointestinal symptomes or regular check-ups, and agreed to participate.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Control group: subjects with no evidence of colorectal adenoma or colorectal cancer * Colorectal adenoma group: Patients with colorectal adenomas greater than or equal to 10 mm in diameter according to the endoscopic presentation as well as histological validation of colorectal adenoma. * Colorectal cancer group: Patients whose biopsy specimen is histologically confirmed as colorectal adenocarcinoma Exclusion Criteria: * Subjects age under 18 years * Previous history of colorectal neoplasms * Patients with high bleeding risk or patients who must maintain anti-coagulant or anti-platelet agents * Denial to participate in this study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Colorectal adenoma are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 463-707, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Gut bacteria may hold clues to why some cancer treatments work better
- Burning the edges: a new way to stop colon polyps from coming back
- Missed Follow-Up colonoscopies: do they raise the risk of advanced growths?
- A 2.2 mm scope could spot cancerous tissue in minutes, not days
- The gatekeepers of tumors: scientists probe how blood vessels let immune cells in
- New Antibody-Drug conjugate put to the test against Hard-to-Treat cancers