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New combo targets gut bacteria to fight advanced colon cancer

NCT ID NCT06356597

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 9 times

Summary

This phase 2 study tests a combination of three drugs (Tislelizumab, Fruquintinib, and Metronidazole) in 33 adults with advanced colorectal cancer that has not responded to prior treatments. The study focuses on patients with high levels of Fusobacterium nucleatum in their stool. The goal is to see if this combo can slow cancer growth and improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai First People's Hospital

    Shanghai, China

  • Shanghai Ninth People's Hospital

    Shanghai, China

Conditions

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