New combo targets gut bacteria to fight advanced colon cancer

NCT ID NCT06356597

First seen Feb 28, 2026 · Last updated May 08, 2026 · Updated 7 times

Summary

This study tests a combination of three drugs (Tislelizumab, Fruquintinib, and Metronidazole) in 33 adults with advanced colorectal cancer that has a high level of a specific gut bacteria called Fusobacterium nucleatum. The goal is to see if this treatment can slow or stop cancer growth. Participants must have already tried at least two prior standard treatments.

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Contacts and locations

Locations

  • Shanghai First People's Hospital

    Shanghai, China

  • Shanghai Ninth People's Hospital

    Shanghai, China

Conditions

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