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New vaccine combo targets hard-to-treat cancers

NCT ID NCT04117087

First seen Jan 04, 2026 · Last updated May 21, 2026 · Updated 18 times

Summary

This early-phase study tests a vaccine targeting mutant KRAS proteins, combined with two immunotherapy drugs (nivolumab and ipilimumab), in patients with colorectal or pancreatic cancer that has been surgically removed. The goal is to see if the combination is safe and boosts the immune system's ability to fight these cancers. The study involves 27 participants and focuses on safety and immune response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

Conditions

Explore the condition pages connected to this study.