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Norway launches massive colorectal cancer screening showdown: which test saves more lives?

NCT ID NCT01538550

Prevention Sponsor: Norwegian Institute of Public Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large pilot study in Norway is comparing two common colorectal cancer screening methods—flexible sigmoidoscopy (a one-time scope exam) and biennial fecal immunochemical testing (a stool test)—to see which works best for the general population. Over 140,000 men and women aged 50-74 are taking part. The goal is to find the most effective way to reduce colorectal cancer deaths and improve screening services nationwide.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
flexible sigmoidoscopy and fecal immunochemical test (iFOBT)
What this could lead to
If successful, this could help determine the most effective screening strategy for colorectal cancer, potentially reducing deaths from the disease on a national level.
What could go wrong
This is a pilot study comparing screening methods, not testing a new treatment. Results may not apply to other populations, and screening itself carries risks like false positives or complications from follow-up procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140,000 people

The number who actually took part.

Started

Mar 2012

Expected to finish

Dec 2034

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 74 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * men and women * age 50-74 years * living in defined geographic areas in South-East Norway (catchment areas for two hospitals) Exclusion Criteria: * previous colorectal cancer

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Conditions

The condition(s) this trial relates to.

adenoma colorectal adenoma colorectal cancer colorectal neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenomas Colorectal cancer

Contacts and locations

Locations

  • Bærum County Hospital

    Rud, 1309, Norway

  • Moss Hospital

    Oslo, 1535, Norway

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