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New Bacteria-Based combo shows promise in advanced cancers

NCT ID NCT04208958

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This early-phase study tested a new treatment called VE800, made from live bacteria, combined with the immunotherapy drug nivolumab in 56 people with advanced or metastatic cancers like melanoma, stomach, and colorectal cancer. The main goals were to check safety and see if tumors shrank. The study is complete, and results help guide future research on using bacteria to boost the immune system against cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor Scott and White Center for Advanced Heart and Lung Disese

    Dallas, Texas, 75246, United States

  • Florida Cancer Specialists

    Sarasota, Florida, 34232, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • Huntsman Cancer Institute and Hospital

    Salt Lake City, Utah, 84112, United States

  • Indiana University Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • John Theurer Cancer Center

    Hackensack, New Jersey, 07601, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • New York University Medical Oncology Associates

    New York, New York, 10016, United States

  • Pacific Hematology Oncology Associates

    San Francisco, California, 94115, United States

  • Swedish Medical Oncology - First Hill

    Seattle, Washington, 98104, United States

  • The Angeles Clinic and Research Institute - West Los Angeles Office

    Santa Monica, California, 90404, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • The University of Chicago

    Chicago, Illinois, 60637, United States

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of California Los Angeles

    Santa Monica, California, 90404, United States

  • Washington University School of Medicine Siteman Cancer Center

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.