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Which pill do patients prefer? study compares two chemo options for colorectal cancer

NCT ID NCT00905047

Symptom relief Sponsor: Centre Oscar Lambret Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 2 times

Summary

This study looked at two oral chemotherapy drugs, Xeloda and UFT with folinic acid, in 89 people with advanced or metastatic colorectal cancer. The main goal was to see which treatment patients preferred after trying both. The study also checked how safe each drug was. Results help doctors understand patient preferences when choosing between these two treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

89 people

The number who actually took part.

Started

Nov 2005

Finished

Sep 2011

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Locally advanced or metastatic colo-rectal cancer * Age \> or = 18 years old * PS-WHO \< or = 2 * Polynuclear neutrophil leukocytes \> or = 1500/mm3, platelets \> or = 100000/mm3 * Total bilirubin \< or = 3 ULN, ASAT-ALAT \< or = 2.5 ULN * Effective contraception * Written informed consent signed Exclusion Criteria: * Concomitant radiotherapy * Contraindication to fluoropyrimidines * Treatment with sorivudine and its chemical analogs such as brivudine * Severe hepatic insufficiency * Severe renal insufficiency * Pregnant or lactating woman * Hypersensitivity to capecitabine, 5FU, tegafur or one of its excipients

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal cancer colorectal neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer

Contacts and locations

Locations

  • Centre Hospitalier

    Armentières, 59280, France

  • Centre Hospitalier

    Roubaix, 59100, France

  • Centre Hospitalier

    Valenciennes, 59300, France

  • Centre Hospitalier Regional

    Lille, 59035, France

  • Centre Hospitalier de Béthune

    Beuvry, 62660, France

  • Centre Hospitalier de CHOLET

    Cholet, 49300, France

  • Centre Joliot-Curie

    Saint Martin Les Boulogne, 62280, France

  • Centre Leonard de Vinci

    Dechy, 59187, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Centre Paul Papin

    Angers, 49033, France

  • Clinique des Dentellieres

    Valenciennes, 59300, France

  • Hopital Saint Vincent de Paul

    Lille, 59020, France

  • Polyclinique du Bois

    Lille, 59000, France

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