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This study tested whether combining a healthy diet, exercise, and the diabetes drug metformin can reverse frailty and obesity in older veterans aged 65-85. 114 participants were enrolled. The goal was to improve physical function and strength, not to cure the underlying condition…

This study tested whether remote hearing care (telehealth) works as well as in-person clinic visits for older adults who already use hearing aids. About 339 people aged 70-84 took part. Researchers measured how many hours a day they used their hearing aids and how satisfied they …

This study tested whether a fermented milk drink containing a specific probiotic (Lactobacillus casei Shirota) could help elderly Taiwanese people with sarcopenia—age-related muscle loss. Researchers measured changes in gut bacteria, muscle strength, and walking speed in 132 part…

This study tested a blood pressure monitoring system to help older adults (65+) take their hypertension medication as prescribed. 200 participants used the system for 6 months, with one group also getting extra tips. The goal was to see if the system improved medication adherence…

This project adapted a program originally designed for nursing homes to help assisted living residents with dementia improve their oral hygiene. The goal was to reduce harmful mouth bacteria that can lead to pneumonia. Over 1,400 residents took part, and community dental hygienis…

This study looked at whether rapamycin, a drug used to prevent organ rejection, can improve heart function in healthy adults aged 70 to 95. Researchers used MRI scans to measure changes in the heart's pumping ability and blood vessel flexibility after 8 weeks of treatment. The go…

This study tested a smart computer system that learns from each doctor's habits to suggest safer prescribing for older patients. About 1,249 patients aged 65+ and 70 primary care doctors took part. The goal was to see if personalized electronic health record reminders help doctor…

This study tested whether a daily supplement called COMP-4 can improve blood vessel function and reduce signs of aging in 32 healthy adults aged 18-39. Participants took the supplement for 14 days, and researchers used ultrasound to measure blood vessel dilation and blood tests t…

This study looked at whether hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — could improve blood flow, brain function, and fitness in healthy adults aged 65 and older. Sixty-two participants received HBOT sessions, and researchers measured chan…

This study looked at whether a 10-week Taekwondo program could improve physical and mental function in adults aged 60 and older. Forty participants were split into a Taekwondo group (training twice a week) or a waiting-list group. Researchers measured balance, strength, fitness, …

This study looked at whether having a dental professional clean the teeth of older adults in their own homes can prevent root cavities. The researchers enrolled 194 people aged 65 and older who needed help with daily care. They compared those who got professional cleaning plus hi…

This pilot study tested whether a telehealth program combining strength training, balance exercises, and nutrition advice could help older men at high risk for falls and fractures. Forty-five men aged 60 and older participated. The goal was to see if the program was practical and…

This study tested whether a chicken extract and a peptide supplement could help prevent memory and thinking decline in older adults without dementia. 276 people aged 55-75 with either mild memory concerns or mild cognitive impairment took the supplements or a placebo for two year…

This study tested a medication care plan to reduce falls in 398 rural adults aged 60 and older. Participants got a personalized plan to safely stop or reduce medications that increase fall risk. Researchers tracked falls and injuries over time to see if the plan helped prevent ac…

This study tested a 4-week program called Zinde Zihin ("Fit Mind") in 62 older adults living in nursing homes. The program included brain games, exercise, nutrition advice, and stress management. Researchers measured changes in Alzheimer's risk scores and found that the program m…

This study tested whether a non-invasive brain stimulation technique called tDCS could improve balance and thinking in older adults who have fallen at least twice in the past year. 118 participants received either real or fake stimulation over 20 sessions in four weeks. The goal …

This study tested a 4-week breathing exercise program in 30 healthy men aged 60-80. Researchers measured changes in diaphragm thickness, fatty liver density, walking ability, and quality of life. The goal was to see if simple inspiratory muscle training could improve these age-re…

This study tested whether a smartwatch and weekly health coaching could help people caring for a loved one with dementia improve their sleep, activity, and mood. Twenty-one caregivers wore an Apple Watch to track their sleep and activity, received personalized feedback through a …

This study tested whether a 12-week cognitive behavioral therapy (CBT) group program is practical and well-liked by older adults (50+) living with HIV. The program aimed to help participants better handle stress related to aging and HIV, and encourage healthy behaviors like physi…

This study looked at whether a year of special strength training could help older adults living in nursing homes. 27 people took part, doing exercises that focused on moving weights quickly. The goal was to see if it improved their muscle mass, strength, physical abilities, and t…

This study tested whether virtual reality (VR) experiences are practical and helpful for seriously ill older adults living in nursing homes. Researchers offered two types of VR—computer-generated and film-based—to 52 residents. They measured common symptoms like pain, anxiety, an…

This study looked at whether an 8-week program of social activities over video calls could improve quality of life and reduce loneliness in older adults, including those with mild memory problems. About 99 people aged 65 and older took part. The results help us understand if simp…

This study tested a gel filler called STYLAGE® XXL to restore lost volume in the mid-face (cheek area) of 90 adults aged 30 to 65. Half received the filler, half got no treatment. The main goal was to see if the filler improved cheek volume more than doing nothing after 24 weeks.…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can enhance computer-based brain training in older adults (60+) with recurrent depression. The goal was to improve thinking skills like memory and planning. The trial involved 16 participants and me…

This study looked at whether high-intensity interval training (HIIT) — short bursts of intense exercise with rest in between — can improve physical fitness in older adults. 39 people aged 60 and older took part in a structured HIIT program. Results showed significant gains in mus…

This study explored whether music improvisation training can improve self-regulation and brain health in older adults, including those with mild cognitive impairment. Fifty-three participants aged 60 and older with little to no music background took part. The goal was to see if i…

This study tested a 12-week exercise program called Vivifrail in 80 elderly residents of long-term care facilities. Participants were assigned to either the exercise group or a control group. The program aimed to improve physical performance, grip strength, and reduce fall risk. …

This study tested four topical products to see if they could improve facial skin longevity and reduce wrinkles over eight weeks. A total of 132 healthy adults aged 40 to 65 used the products and provided feedback through questionnaires and skin imaging. The main goal was to measu…

This study tested whether a hyaluronic acid filler called RHA Redensity can improve fine lines on the cheeks caused by aging and sun damage. Twenty adults aged 31 and older with noticeable cheek lines received the filler and were followed for 8 weeks. The goal was to see if the l…

This study tested a new gel called IPN-21-SENSE, made from hyaluronic acid, to restore lost volume in the mid-face (cheek area) due to aging. 89 adults aged 30 to 84 who wanted mid-face correction were randomly assigned to receive the gel or no treatment. The main goal was to see…

This study looked at whether taking a daily high dose of vitamin D3 (10,000 IU) for 12 weeks could improve muscle strength and muscle mass in older adults (60+) with obesity. 29 participants from southern Mexico completed the trial. Researchers measured handgrip strength, muscle …

This study looked at whether an 8-week group exercise program could improve physical abilities and sleep in older adults aged 65 to 90. Eighty participants from community sites in Taiwan either joined the exercise program or continued their usual activities. The program included …

This small study tested a 12-week machine-based Pilates program in 16 active older adults (ages 55-75) with moderate low back pain. Participants did two sessions per week. The goal was to see if this approach could improve quality of life and reduce pain. Results may help design …

This study tested a program called DAPPER for African American women aged 50 and older who had pain, depressive symptoms, and trouble moving around. Participants received 8 nurse visits at home to help manage their pain and mood. The study measured changes in pain intensity and d…

This study looked at whether a group Nordic walking program could improve the physical and mental health of older adults (65+) who were evacuated from their homes to Haifa. Twenty-four participants walked together twice a week for two months using special poles. Researchers measu…

This study looked at whether gardening activities (horticultural therapy) can reduce loneliness and improve life satisfaction in elderly people living in nursing homes. 54 adults over age 60 took part, with some doing gardening and others not. The goal was to see if interacting w…

This study tested whether 20 hours of executive function training could improve thinking skills and reduce mental ups and downs in adults over 40 with HIV-related cognitive problems. 119 participants were split into a training group and a no-contact control group. The goal was to…

This study looked at whether acupressure—a gentle, non-invasive technique—can improve sleep, quality of life, and feelings of hopelessness in older adults living in nursing homes. Fifty people aged 65 and older took part. One group received acupressure three times a week for four…

This study looked at whether taking Beta Glucan 500 capsules daily for 12 weeks could affect markers of biological and immune age in healthy adults aged 40 and older. Sixty participants took the supplement, and researchers measured changes in their DNA-based aging clocks. The goa…

This study looked at how age and body fat affect inflammation in 100 veterans. Researchers wanted to see if losing weight and doing aerobic exercise could lower inflammation. Participants followed a weight loss and exercise program to test these effects.

This study looked at 64 adults over age 65 to see if easy, bedside checks of physical function and muscle size can predict overall fitness. Participants did a cycling test to measure their maximum oxygen use. The goal was to find simple ways to estimate fitness without complex eq…

This study looked at how sleep affects balance and thinking in healthy adults aged 65 and older. Over six weeks, 18 participants wore an OURA ring and kept a sleep diary while doing balance and memory tests. The goal was to understand daily connections between sleep, mobility, an…

This study aimed to find out how often low blood sugar (hypoglycemia) happens in older adults (over 64) with diabetes who live in long-term care facilities. Researchers used a continuous glucose monitor (CGM) worn for 10 days to track blood sugar levels in 86 participants. The go…

This study looked at how one session of exercise changes the brain's response to insulin in adults aged 40 to 80 who are overweight or obese. Researchers used MRI scans to measure brain activity and tested memory and thinking skills. The goal was to learn more about how exercise …

This study looked at how a short-term fiber supplement (inulin) changes gut bacteria and metabolism in people with COPD compared to healthy older and younger adults. Researchers measured fatty acid production and gut health markers from blood and stool samples. The goal was to un…

This early-stage study tested whether drinking beetroot juice (rich in natural nitrates) could improve blood vessel stiffness and brain blood flow in 16 adults aged 50-79. Participants were randomly assigned to drink either nitrate-rich or nitrate-free beetroot juice. The goal wa…

This study looked at whether training the muscles used for breathing can improve heart health and mood in women who have gone through menopause. Researchers tested 28 women aged 50 to 75 by having them do breathing exercises and measuring how their bodies responded during walking…

This study followed 81 adults who had stroke-like symptoms to see how damage to the blood-brain barrier relates to white matter changes in the brain. Participants had MRI scans and thinking tests over 6 years. The goal was to learn more about these changes, not to test a treatmen…

This study looked at how the brain processes emotional scenes in healthy younger and older adults. Researchers used functional MRI to compare brain activity when participants judged emotions versus when they identified action tendencies. The goal was to understand how normal agin…

This study looked at how menopause affects brain chemistry and Alzheimer's risk in 120 postmenopausal women aged 50-70. Researchers used brain scans and memory tests to see how the brain's cholinergic system responds to hormone changes. The goal is to understand why some women ha…

This study looked at how age changes brain wave patterns during anesthesia with desflurane. Researchers monitored 47 adults having surgery, from young to elderly, and analyzed their brain activity. The goal was to understand how aging affects the brain's response to anesthesia, n…

This study looked at how eating too few or too many calories affects muscle maintenance in healthy middle-aged adults during short periods of inactivity. Researchers measured muscle protein production and muscle size changes in 23 participants. The goal was to understand the role…

This study looked at physical resilience—the ability to recover—in 297 adults aged 60+ who had planned knee replacement surgery. Researchers measured steps, pain, thinking skills, and immune responses before and after surgery to understand what helps people bounce back. No new tr…

This study looked at whether daily breathing exercises could improve memory and reduce Alzheimer's risk in healthy adults aged 50-70. Participants did brain training and either relaxing or alertness-boosting breathing exercises for 10 weeks. Researchers measured changes in blood …

This study tested whether a 6-month program combining physical and mental exercises, special foods, and vaccines could improve the health of elderly people living in nursing homes. 90 residents aged 70 and older took part. The main goal was to see if the program was practical and…

This study looked at whether medications with a high atropine load (a measure of certain drug effects) increase the risk of confusion after hip fracture or joint replacement surgery in older adults. Researchers tracked 161 patients and assessed confusion using a standard scale. T…

This study looked at how cannabis affects thinking, balance, and walking in 25 older women, some with HIV and some without. Researchers gave participants either cannabis or a placebo and tested their walking speed, balance, and attention. The goal was to understand why cannabis u…

This study looked at whether older adults with overweight or obesity could follow two different eating plans for 9 months: eating fewer calories overall or eating only during a specific time window each day. The goal was to see if these plans were practical and safe for seniors. …

This study looked at why older adults with type 2 diabetes or who are hospitalized lose muscle size, strength, and function faster. Researchers measured leg muscle mass and knee strength in 95 participants. The goal was to find new targets for treatments to slow down muscle loss …

This study looked at how a very low-carb ketogenic diet compares to a Mediterranean diet for bone health and muscle function in older adults. Twelve postmenopausal men and women participated in this short-term pilot trial. The goal was to gather initial data on safety and benefit…

This study looked at whether eating only during certain hours of the day (time-restricted eating) can improve blood vessel and brain function in older adults. 32 people aged 55 to 80 took part. Researchers measured changes in brain blood flow and electrical activity to see if thi…

This study looked at how periods of reduced activity, like after surgery or injury, affect blood vessel function and muscle health in older adults. Researchers measured blood flow in the arm and leg arteries to understand the role of oxidative stress. The goal is to find ways to …

This study aimed to create online mindfulness and lifestyle education programs for adults aged 50+ who have memory concerns but normal thinking skills. Participants joined focus groups to share their views on healthy living and web-based programs. Their feedback helped refine the…

This study looked at whether drinking ketones can improve how muscles work in healthy young (20-25) and elderly (65-85) men. Participants drank a ketone drink and then had their muscle function measured using special MRI scans, tracer infusions, and exercise tests on a bike and s…

This study tested a social robot that leads activities like trivia and reminders for people with Alzheimer's or other dementias living in assisted care. 26 residents, family members, and staff took part to see if the robot helped with engagement and mood. The goal was to understa…

This study looked at fat tissue from healthy young (18-30) and older (65+) adults to see how blocking a protein called MetAP2 affects aging-related changes in the lab. Researchers measured markers of aging and fat tissue quality. The goal was to understand aging better, not to te…

This study looked at whether a four-week moderate strength training program could help healthy men aged 60-75 improve their diaphragm thickness (a key breathing muscle), reduce liver fat, and enhance quality of life. Thirty participants were split into an exercise group and a con…

This study looked at how short-term pain affects the ability to learn and remember new movement patterns in 61 healthy young and older adults. Researchers tested walking patterns and memory tasks to see if pain impairs learning and if older adults are more affected. The goal is t…

This study looked at how inflammation impacts feelings of pleasure and motivation in older adults (ages 60-80) with anxiety. Researchers used brain scans and computer tasks to measure these effects. The goal was to better understand the link between anxiety, inflammation, and los…

This study looked at how aging changes certain enzymes (proteins) in the blood and colon. Researchers collected blood and colon tissue samples from 21 adults, both younger (18-50) and older (65-80). They also checked whether the HIV medications tenofovir and emtricitabine affect …

This study looked at how quickly a short break from exercise (3 days of reduced activity) affects blood vessel function and blood sugar control in active older adults compared to younger adults. Researchers measured changes in blood sugar after a meal before and after the inactiv…

This pilot study explored whether combining lifestyle changes, risk factor management, medications, and supplements could improve motor, cognitive, and immune function in aging adults. 23 sedentary adults aged 50-70 participated. The main goal was to see if the program was feasib…

This study measured flexibility, muscle endurance, and posture in 38 women aged 18-65 who regularly do Reformer Pilates. Researchers used tests like the sit-and-reach and a 3D body scanner to see how these measures change with age. The goal was to understand the effects of Pilate…

This study tested whether specially designed tablet games, called VibrantMinds, can measure and improve cognitive skills in older adults with mild cognitive impairment or dementia. 26 participants aged 65 and older played the games, and researchers tracked changes in thinking, mo…

This study looked at how healthy older adults (65+) handle extreme heat compared to younger adults (18-35). Researchers measured body temperature and heart function during simulated heat wave conditions. The goal was to understand the risks and help protect seniors during hot wea…

This study tested whether a drug that lowers heart rate (ivabradine) can improve the flexibility of arteries in healthy people. 30 volunteers aged 25-65 with a resting heart rate of 70 or higher took either the drug or a placebo for 8 days. Researchers measured artery stiffness a…

This study tested a new ultrasound technique called Fast Cerebral Pulsatility Imaging (FCPI) to measure tiny brain movements in healthy adults. Researchers compared younger and older participants to see how these pulsations change with age. The goal was to better understand norma…

This study looked at whether high-intensity rehabilitation can improve recovery for older adults in skilled nursing facilities after a hospital stay. Over 4,300 people took part. The goal was to see if this approach works and can be put into practice.

This study tested whether a specially designed video game could help adults aged 45 and older stay healthy and active as they age. Over 500 people in Spain were randomly assigned to play the game or read online information about active aging. Researchers measured their health sta…

This study tested whether healthcare workers who wear a special suit that mimics the physical challenges of aging become more empathetic toward older adults. 82 nurses, therapists, and other staff from four nursing homes either attended a class on aging or also wore the suit. Tho…

This study looked at whether the diabetes drug metformin can slow aging in people without diabetes. Researchers wanted to see if the drug works differently depending on how sensitive a person is to insulin. Over 12 weeks, 101 healthy adults took either metformin or a placebo. The…

This study enrolled 1,000 adults aged 30 and older from North Carolina to measure their physical fitness, thinking skills, and collect blood samples. Researchers will track changes over two years to learn what factors are linked to healthy aging. No treatments or medications are …

This study tested two ways to help emergency room doctors prescribe safer medications for older adults (age 65+). The goal was to reduce the use of potentially inappropriate medications that can cause harm. Researchers compared giving doctors simple reports versus active feedback…

This study looked at 556 people to understand why some with early age-related macular degeneration (AMD) have trouble seeing in the dark. Researchers used advanced eye imaging to map how changes in the retina affect night vision recovery. The goal is to find better ways to measur…

This small pilot study looked at whether adding insect-based protein biscuits to a supervised exercise program could improve heart health in adults aged 60 and older. Thirty participants ate either insect or regular biscuits after exercise for 28 days. The study measured changes …

This study looked at whether it is possible to collect blood, stool, and survey information from women aged 65 and older who are taking aromatase inhibitors for breast cancer. The goal was to see how this common hormone therapy might affect aging and gut bacteria. 94 women took p…

This study looked at how emotional skills of young women (45 or younger) with non-spreading breast cancer and their partners affect their ability to adjust to the disease. Over 390 couples were followed from chemotherapy through recovery. The goal was to understand how emotions i…

This small pilot study looked at how quickly flavonoids from blueberries enter the body and whether they can reduce inflammation in older adults (65+) who have mild depressive symptoms. Six participants each tried two different doses of blueberry powder. The goal was to see if hi…

This study looked at how the COVID-19 pandemic affected the health of people aged 75 and older and their caregivers. Researchers analyzed medical records and interviewed participants to understand changes in health, daily routines, and care needs. The goal is to find ways to impr…

This study tested whether imagining a finger movement (motor imagery) combined with a gentle electrical current to the brain (tDCS) could improve learning of a complex finger sequence. 64 healthy young and elderly adults participated. The goal was to see if this combination boost…

This study looked at whether a gentle, non-invasive brain stimulation technique can help older adults learn and remember complex walking tasks, like stepping over obstacles. Researchers used MRI scans to see how the brain changes with practice. The goal is to find new ways to mak…

This study tested a plant-based supplement called LLP-01 in 32 healthy adults aged 50-75. Researchers measured changes in blood proteins related to inflammation and heart health, along with grip strength, weight, and well-being. The goal was to see if the supplement could improve…

This study looked at whether watching exercise videos before doing the exercises (called Action Observation Therapy) helps older adults improve their thinking, balance, fatigue, and physical function. 162 people aged 65 and older took part. Some did regular exercise, some watched…

This study looked at how limiting eating to certain hours of the day (time-restricted eating) affects energy use and daily body rhythms in overweight adults aged 65 and older. Researchers used wearable rings and blood tests to track changes in metabolism, sleep, and activity. The…

This study tested whether a supplement called L-Citrulline can improve blood vessel function in the brain and body of healthy young and older adults. Twenty participants took the supplement and had their brain activity and blood flow measured using special scans. The goal was to …

This study looked at whether a 12-week adapted CrossFit program could improve balance, mobility, and leg strength in older adults living in the community. Sixty participants were randomly assigned to either the exercise program or their usual routine. The main measure was the Tim…

This study surveyed 47 older adults (65+) in France to understand how much they know about cannabidiol (CBD) and whether they use it. The goal was to gather information to help guide safe CBD use and prevent potential side effects in this age group. Participants completed a quest…